m-chrzan

Not that I know of, and I grant that this is an unknown, and we could end up learning about extremely bad 20-/30-/40-year effects in the future. That said, there are very clear, very significant, and very well studied harms of cigarette smoking. Research is being done on vaping, and so far all harms identified are significantly lower than smoking.

>Also nicotine itself is not without harm.

Sure, and thanks for the paper. I'm not well versed in bio enough to tell the significance of everything in there, but, correct me if I'm wrong, for the most part this is showing there exist harms, but they're not particularly well quantified yet, especially in terms of human subjects? For this to really matter, you'd need to quantify the surplus of nicotine you get from vaping vs. smoking, and then compare the relative harms of those two doses. Could be that 5x the dose causes 5x the harm, or could be that the smoking dose passes some threshold, and 5x the dose from vaping is just marginal additional harm on top of that. And then still compare that to the other differences between smoking and vaping in terms of harm.

>Most people [...] need about an hour break in between smokes.

I've never seen anything like that. When there's a group of social smokers standing around, it's very common for something like "Oh, I just finished mine and you're only half-way through yours, I'll light up another one to keep you company" to happen. I've seen plenty of people who aren't chain smokers (yet), but can easily go through 2-4 cigarettes in a row if they're suddenly in a stressful situation and smoking "to relax".

>So in terms of pure addiction I would 100% argue that cigarettes are better than vaping.

But that's not a metric that's in any way helpful for a health decision. Nicotine in and of itself is not particularly physically harmful - it's toxic at high doses and elevates heart rate for a bit, but that's about it. The delivery method is what causes most of the harm, and smoking is 100% known to cause a lot of harm in a lot of different ways. And "With vaping that limit is completely gone" is also not accurate. Unlike the Navier-Stokes equations, dopamine receptors don't experience infinite blowup in finite time. So choosing a delivery method based on the amount of nicotine taken daily is not going to change much in terms of addiction (if you're already heavily addicted, you'll remain heavily addicted), but can have a huge impact on physical health.