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Comment by dekhn

how could they do ab initio? They depend on multiple sequence alignments.

If I'm mistaken about this then I'll happily take back what I said, but there's no way that AF2 could work wihtout MSAs, therefore, it is not ab initio.

Ah, OK checked the paper again. They're working on the "template" category which means there is structure-sequence information... maybe CASP organizers consider this ab initio ? The paper never mentions anything about ab initio predicitons. Is that what you're saying, that template methods are ab initio?

parent dekhn 5 years ago

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