zachthewf

Joined 15 years ago

Karma
1,734
Submissions
336
Member since
Mar 10
interested in accelerating drug discovery and medicine development

currently @ boltz bio, former yc founder

zachocean.com

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Recent submissions

Comment · 1 month ago
What are the innumerable cruel and harmful things that Google has done to society?
Comment · 1 month ago
Thanks for posting - have been following from afar and very interested in this area. Sorry for the naive questions, I am a software guy new to biotech.

- How have things looked since passage? Has there been a lot of interest from companies and patients or is demand the bottleneck? Not that many people in Montana...

- What sort of new business models does this open up? e.g. Roivant for abandoned phase 1 assets?

- Does this lower the barrier for treating new indications, e.g. age related conditions like sarcopenia?

- Any particular rules on telehealth?

Comment · 1 month ago
It's a relevant question but not a "gotcha". Businesses are not equivalent in complexity and no one at Andon would claim that running an effective vending machine business is similar to running Apple or Jane Street. There is some level of complexity and other characteristics that AI can maybe handle today. That doesn't mean CEOs should be worried about their jobs more generally.
Comment · 1 month ago
Comment · 1 month ago
I’ve found Sol performance to be incredibly spiky. It has tremendous IQ and can fix very difficult bugs. But it is horrible at design (both visual and system design), anything that involves thinking about users or UX, and massively overcomplicates almost all work.
Comment · 1 month ago
I’d be willing to bet any amount of money that there will be ~the same or more people doing physical labor in 10 years than today.
Comment · 1 month ago
Looks interesting. What's your plan on the legal front? Bet the company on the compounding lawsuits breaking in your favor, or do you have a backup plan?

BTW: when you say you manufacture the drugs, I assume that means you're buying from an API supplier, but do you actually mean you're synthesizing it yourself?

Comment · 2 months ago
Segment had a $3B+ exit to Twilio back in 2020.
Comment · 2 months ago
Nope, not parody. Very accurate description of early-2020s consumer TTS websites.
Comment · 2 months ago
FYI: If you have a company that you are shutting down, you too can sell your data to the labs. Companies will help you do this. If you have a company with a handful of people and you wrote code, collaborated in Slack, and used task management tools for a few years, you can probably sell this data for $50k or so.

You can also do this if you're not shutting down, but it's probably not worth it.

Comment · 4 months ago
I'm open-minded to arguments about AI being a financial bubble and a bad business.

I'm not open-minded to arguments about utility, given that I personally witnessed LLMs evolve from interesting but useless toys to insanely helpful tools I use every day.

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