rpkoven

My thought is yes. There has to be neuronal death as the neuron becomes less sensitive to insulin and metabolize glucose.

The dynamic, wave-like model of aging aligns with the concept of quasi-programmed aging, which suggests that aging is not merely the result of accumulated damage, as proposed by the wear-and-tear model. Instead, aging reflects the unintended continuation of biological programs that were originally optimized for growth, development, and reproduction. These programs, including pathways such as mTOR, become dysregulated over time, driving aging and the onset of age-related diseases.

Our genes are programmed for growth, growth gets out of control, leading to our death

What is the cadence of giving blood to offload iron?

So basically I don’t have to exercise anymore?

No pain, no gain.

Article makes sense. No hacks.

Interesting that they could quantify the differences in energetic output from a mitochondrial level. I guess it’s time to start running again.

Vigorous exercise enhances the heart's plasticity, which refers to its ability to adapt and remodel itself in response to increased physical demands. This includes increasing the size of the heart chambers, improving the heart muscle's ability to contract, and reducing stiffness in the heart walls

In the first four hours following protein ingestion, the study observed a 20% higher rate of muscle protein synthesis in participants who consumed 100 grams of protein compared to those who ingested 25 grams. This difference became even more pronounced during the 4–12 hour postprandial period, where the muscle protein synthesis rates were 40% higher in the 100-gram group. Overall, this equated to a 30% larger synthetic response after consuming 100 grams of protein, as opposed to 25 grams.