rfinney
Joined 8 years ago
Karma
414
Submissions
135
Member since
Jul 23
Recent submissions
Comment · 7 years ago
Comment · 7 years ago
India started developing nuclear weapons in the 1950s and first tested a nuclear bomb in 1974.
Comment · 7 years ago
"non major liberal cities"
I think the "me too" thing proved the coastal elite were part of the problem.
Comment · 7 years ago
This provides access to hundreds of public and tens of thousands of restricted access cancer genomes (and often the matching "normal" samples): so you can see and visually verify mutations. Interestingly, too, you can check out germline polymorphisms which might predispose someone to get cancer.
Basically all the work is done in the browser : gzip decompression, custom parsing of sequencing alignment, png generation, etc. Lots of data are pushed to the client at load time like gene location information for genome build "hg38" (the latest). Server only provides reference sequence and sample genomic alignment "slices" for the region of interest. So, all the state is handled in the browser, server only provides trivial "wget" requests.
It is mostly wasm (source is C compiled with emcc). The front page is the requisite html/javascript start page. Pages are created in wasm code and pushed to JS for updating the DOM. Lots of calls to emscripten_run_script("your javascript here"). DOM manipulation straight from Rust/Go/C would be cool but it is not here yet.
Upside is server simplicity and security ... and no downloading and setting up complicated software.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987889/
Code is done by the government so it's public domain. (Your tax dollars at work !)
Comment · 7 years ago
NCI Chromatic - Cancer Genomes with WebAssembly:
Imagine European idealists prosecuting Clinton, Bush and Obama for "war crimes"? No way.