readittwice
Joined 10 years ago
Joined 10 years ago
Do I have this right that CAR T-cells have this engineered B-cell/antibody like receptor that recognizes antigens only on the cell membrane. While the regular T-cell receptor can look into cells as well? And that's why the T-cell receptor is potentially better at recognizing solid cancers?
So cancers usually create this immunosuppresive environment, wouldn't this stop this engineered T-cells as well?
It seems the cost price differs from country to country because of different production costs and other factors (maybe shipping).
[1] https://www.politico.eu/article/astrazeneca-vaccine-cost-hig...
Almost no one would argue that because AFAIK that never happened. Pretty sure people would argue that way as soon as this happens.
AZ is selling at cost, so they are not making a profit from the vaccine atm. So that statement should be trivially true.
That's why it was considered "news" when it was reported that one particular contract was signed by the UK one day after the EU. But that's not the full story, since the UK had binding contracts with AZ well before that.
"The link also says they wouldn't export EU manufactured vaccines, except Italy blocked an export to Australia a couple of weeks ago." I haven't seen that claim in the article you linked.
"However, the key lies in an earlier agreement that AstraZeneca made back in May with the U.K., which was a binding deal establishing “the development of a dedicated supply chain for the U.K.,” an AstraZeneca spokesperson said."
Quote is from this article: https://www.politico.eu/article/the-key-differences-between-...
"And as POLITICO reported last week, the non-redacted version of the contract shows that the EU also waived its right to sue AstraZeneca in the event of delivery delays."
Quote from this article: https://www.politico.eu/article/the-key-differences-between-...
That explanation doesn't make a whole lot of sense since the delay was only a few weeks for Biontech/Pfizer or Moderna. As you mentioned, AZ is not even approved in the US. Europe would need to vaccinate around 50M people in a few weeks.
EU politicans know that the EU has failed at procurement. They now try to cover that up by blaming AZ and explaining delays with additional safety measures.
"However, the key lies in an earlier agreement that AstraZeneca made back in May with the U.K., which was a binding deal establishing “the development of a dedicated supply chain for the U.K.,” an AstraZeneca spokesperson said."
Quote is from this article: https://www.politico.eu/article/the-key-differences-between-...
"However, the key lies in an earlier agreement that AstraZeneca made back in May with the U.K., which was a binding deal establishing “the development of a dedicated supply chain for the U.K.,” an AstraZeneca spokesperson said."
This quote is from this article: https://www.politico.eu/article/the-key-differences-between-...
How can someone have their whole (!) genome sequenced already when so far we weren't able to fully sequence the Y chromosome. And this person seems to have a Y chromosome.