Since there are people here that seem to know a bit about this stuff, I will take the chance to ask some naive questions ;)
Do I have this right that CAR T-cells have this engineered B-cell/antibody like receptor that recognizes antigens only on the cell membrane. While the regular T-cell receptor can look into cells as well? And that's why the T-cell receptor is potentially better at recognizing solid cancers?
So cancers usually create this immunosuppresive environment, wouldn't this stop this engineered T-cells as well?
Do I have this right that CAR T-cells have this engineered B-cell/antibody like receptor that recognizes antigens only on the cell membrane. While the regular T-cell receptor can look into cells as well? And that's why the T-cell receptor is potentially better at recognizing solid cancers?
So cancers usually create this immunosuppresive environment, wouldn't this stop this engineered T-cells as well?