mxcrossb
Joined 7 years ago
Karma
1,604
Submissions
435
Member since
Feb 15
Recent submissions
Comment · 5 years ago
I wonder if someday we get even more absurd. Musk wagers company money on the Chiefs to win the Super Bowl, announces this on Twitter, then hedges his bet when Vegas moved the line after a bunch of pro chiefs action. I mean, it’s not like there aren’t hedge funds that do sports gambling already.
Comment · 5 years ago
I always try to use HIV as my point of reference for COVID-19. We got off lucky by that measure. So maybe my pessimism is unfounded, but I really wish we had learned more lessons from HIV.
Comment · 5 years ago
Half a year into the pandemic the president of the United States was filling stadiums was maskless supporters. The WHO seems completely willing to fall on their sword over COVID, and indeed they failed in many ways. But in the long run, we’re seeing a disaster of anti intellectualism around the world, and the next pandemic may be just as bad as this one.
Comment · 5 years ago
Stick a fan in it so I can hear if a background process is being run!
Comment · 5 years ago
More like buying indulgences
Comment · 5 years ago
For the list of mutations, there is a convenient Wikipedia article [1]. For example, the South Africa variant has mutation E484K which means mutate amino acid 484 from Glutamic Acid to Lysine. It’s just that simple; you could even download a spike protein crystal structure from RCSB and try rolling your own mutations!
Why a mutation improves transmission takes a lot of investigating to understand. I am not sure why you were under the impression that we know the mechanisms. If you type something like “E484K molecular dynamics” you can find a lot of computer simulations trying to investigate the mechanism, this is standard biological research. Of course we E484K you have a mutation from a negative to a positive residue, so that might give you a hint why it’s harder for the antibody to stick.
I can assure you that here in Japan we do not care about Trump. Perhaps we should be more grateful to his good support for the Pfizer vaccine, which is the one we are now deploying at scale (after the government here did their own review of the evidence).
Comment · 5 years ago
It seems like the flu virus is the example you want right? Every year the vaccines delivered is a cocktail based on the predicted most common variants, because no one vaccine can protect against them all.
Comment · 5 years ago
This is a reminder that a lot of this comes down to the whims of whoever is staffed at HR. I’ve often read contradictory advice about resumes in articles written by people in charge of hiring. It’s not a big surprise, a lot of these views are arbitrary (though they will insist otherwise!)
Comment · 5 years ago
I am in favor of the current title as it makes it extremely obvious how few HN users actually read an article before commenting.
Comment · 5 years ago
The article isn’t saying they’re happier people…
> Tesla Models X, S, and 3 all have high customer satisfaction ratings on Consumer Reports, with the Model 3 earning a CR Recommended label.
Comment · 5 years ago
I wonder how serializing a novel would mesh with most author’s work flow. I guess most would want to write it first and release monthly an already finished product?
Comment · 5 years ago
> The galactic center, according to the scientists, “provides an ideal” central location for “advanced civilizations to place a powerful transmitter to efficiently send beacons across the entire Milky Way,” in what is yet another advantage to this strategy.
Can anyone comment on this? What is the idea of such a beacon?