michaelhoffman

I understand why this is bad, but I personally would sign up for a Microsoft account anyway. Mainly, I don't want all my stuff in "C:\Users\micha". Is there a way to set your username?

When FASTA was invented in 1985, generally sequencing reads would be about half that.

The simplicity of FASTA seems like a dream compared to the GenBank flat file format used before then. And around the year 2000, less computationally-inclined scientists were storing sequence in Microsoft Word binary .doc files.

A lot of file formats (including bioinformatics formats!) have come and gone in that time period. I don't think many would design it this way today, but it has a lot of nice features like the ones you point out that led to its longevity.

Using machine learning, he counted all of the yurts.

Counting all of the yurts that happen to be using machine learning is a way more difficult problem.

> I assume the author means "out of all the ISAs I know"?

Out of all the ISAs where they know whether it provides integer division or not.

This is not "hard-coded" as I would describe it. It is defined in `gv.el`:

    (gv-define-setter buffer-string (store)
  `(insert (prog1 ,store (erase-buffer))))

Unfortunately, it is marked obsolete since 29.1. The NEWS says:

* Many seldom-used generalized variables have been made obsolete. Emacs has a number of rather obscure generalized variables defined, that, for instance, allowed you to say things like:

    (setf (point-min) 4)

These never caught on and have been made obsolete. The form above, for instance, is the same as saying

    (narrow-to-region 4 (point-max))

This used to be the case until Emacs 24.1, in 2012.

    Passing a nil argument to a minor mode function call now ENABLES
    the minor mode unconditionally.  This is so that you can write e.g.
    
        (add-hook 'text-mode-hook #'foo-mode)
    
    to enable foo-mode in Text mode buffers, removing the need for
    'turn-on-foo-mode' style functions.  This affects all mode commands
    defined by 'define-minor-mode'.  If called interactively, the mode
    command still toggles the minor mode.

When would you need to use rdmsr and wrmsr in a crisis?

I wonder if they swapped the benchmark results somehow. Because on my computer, I get roughly the same times but with {} twice as fast as dict().

I don't think so, but in 2023 "PC" can refer to a whole bunch of different things, and "5150" is precisely clear about what it refers to.

I hope it keeps its blazing-fast startup. I regularly used Paint instead of Photoshop on a system where I had both because Paint starts instantly but Photoshop took a bit.

The Bay Area has inadequate public transport for a metro of its size, but its utility is kind of another universe from the Austin's CapMetro.

This is super cool. I use Emacs `abbrev-mode` for taking contemporaneous notes but autosuggesting words would be great.