mamuninfo

I don't think, it is good idea to think about language and framework first than domain.

If it is prototype or just proof of concept then it is better to use good framework that helps to build quick prototype. May be Django or RoR is best choice if you already know it. But if you have some problem with exiting system like improve system performance or scalability issue then you could think about something else.

In the end, to me need to understand problem first then framework or language but not vice versa.