louden
Joined 12 years ago
Joined 12 years ago
The cost of full body imaging is not just in the scan itself but in the procedures that follow it that require anasthesia (non-zero chance of killing the patient), cause pain and may cause secondary infection. In fact, just being in the hospital or doctors office to get the procedure has a non-zero risk to due to the concentration of sick people there.
My point was not that either side was correct but rather that a simple statement like "more data is always better" is not as simple as they seem to think it is. Those of us who work in this field deal with balancing the risks as best we can so that we can detect the marginal elevated risk of something in a way so that the benefit outweighs the costs (financial, physical and emotional).
Several years ago I worked on a study looking at the spread of bacterial lung infections in long term hospital patient. In order to get the data, we would have to intubate patients that did not need it. In this case, the people who approve these studies rightfully ruled that getting that data would be too painful for the patients to allow.
Biopsies caused by benign findings from a full body scan are not without pain, emotional distress, risk or cost to the patient. Period. It must be weighed against the benefit that the patient would recieve (all in the aggregate, or course).
In the back of Statistical Inference by Casella and Berger, there is a great chart making similar connections between the most common statistical distributions.
There is a lot of rhyming in statistics.
While replacing tires more frequently would reduce the number of blowouts, it would be very wasteful. In the US, DOT inspections are frequent and they look at the tires to make sure they are in good condition.
In this type of cancer, a lower specificity is an acceptable trade off for a very high sensitivity.
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