krasney

The most recent critiques I've seen for intermittent fasting have to do with how it may not preserve lean body mass unless you are extremely conscientious about getting enough protein (and probably resistance training). That is, if you don't get enough protein during your feeding windows, you'll lose lean body mass along with fat mass, which harms body composition. I'd expect to see the TRE arm losing more lean body mass.

Table 2 seems to show this effect. The TRE arm lost more lean body mass and fat mass, although without a difference in visceral fat. If compliance is the issue, I'd be curious to understand what regime can help TRE participants comply with a minimum protein threshold in their diet to minimize the risk of lean body mass loss.