kiterunner2346

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Yesterday or the day before IIRC a fellow "WilsonPaige", https://news.ycombinator.com/user?id=wilsonpaige posted much earlier on Hacker News and, right in front of us, deduced that the combinationn of chloroquin + zinc lozenges would stop the covid-19 virus dead in its tracks. He announced it as such.

In return, ycombinator moderators hellbanned him and deleted some of his posts.

Now it seems WilsonPaige was right and everybody who contradicted him are, at the least, looking foolish and simply wrong.

Chloroquine Is a Zinc Ionophore (2014) ncbi.nlm.nih.gov

8 kiterunner2346 6 years ago 5 comments

Comment · 6 years ago

Why did you delete most of wilsonpaige's posts? All he did is put two things together and come up with an idea that will apparently work. So he's kinda in Neils Bohr's situation with the hydrogen atom: it works, it only works here, I don't know why it works, but it works! Isn't that the essence of creativity?

Why the dunning and shunning? If the women in reasonable shoes on this bbs had any creativity we wouldn't be in a jam with Covid.

Is wilsonpaige so different in this regard from Elon Musk? Musk posts re quinone and is praised and his ideas spread. Wilsonpaige at first doubts the quinone solution, then within hours finds confirming studies, adds to it his experience with zinc antivirals and comes up with a better solution (albeit one w/o an underlying mechanism). Now you've torn his posts up and thrown them away.

Shame!

Comment · 6 years ago

WilsonPaige is right (if not always for the "right" reason):

"Coronavirus Chloroquine & Zinc Treatment":

https://citycourier.org/news/coronavirus-chloroquine-zinc-tr...

Comment · 6 years ago

Lancet Article(February 22, 2020): "Reducing mortality from 2019-nCoV: host-directed therapies should be an option"

https://www.thelancet.com/journals/lancet/article/PIIS0140-6...

from the article:

"In most moribund patients, 2019-nCoV infection is also associated with a cytokine storm, which is characterised by increased plasma concentrations of interleukins 2, 7, and 10, ..."

Comment · 6 years ago

Title: "Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China"

https://www.thelancet.com/journals/lancet/article/PIIS0140-6...

from the Lancet article:

"In view of the high amount of cytokines induced by SARS-CoV,22, 24 MERS-CoV,25, 26 and 2019-nCoV infections, corticosteroids were used frequently for treatment of patients with severe illness, for possible benefit by reducing inflammatory-induced lung injury. However, current evidence in patients with SARS and MERS suggests that receiving corticosteroids did not have an effect on mortality, but rather delayed viral clearance.27, 28, 29 Therefore, corticosteroids should not be routinely given systemically, according to WHO interim guidance."

Comment · 6 years ago

The key may not be a vaccine but simply staying alive. Covid-19 kills with a "cytokine storm":

cytochine release syndrome(cytokine storm):

https://en.wikipedia.org/wiki/Cytokine_release_syndrome

Article discussing coronavirus et al and cytochine storm:

"Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China"

https://www.thelancet.com/journals/lancet/article/PIIS0140-6...

From the article:

Curcumin has been shown to suppress the cytokine storm.

https://www.ncbi.nlm.nih.gov/pubmed/25600522/

Curcumin is found in the spice turmeric and is available in most grocery stores. Today you can buy a pound of turmeric powder for ~$6. You can buy curcumin tablets in the health & fitness section.

Other anti-inflammatory agents (NSAIDS(aspirin, buprofen, naproxen),prednisone, etc.) are not as effective.

In India children are often given a daily teaspoon of turmeric (curcumin) in milk or water. India suffered much lower SARS deaths (there are confounding factors, e.g. India's high summer heat). I expect the same to happen with covid-19.

Comment · 6 years ago

Years ago one doctor (IIRC a general practioner) noticed that all his diabetes patients taking metformin never got cancer. So he wrote a letter about it. I've lost the cite.

Today everyone, even doctors, knows that high blood sugar levels increase the odds of cancer AND diabetes. That's why everyone and his dog is taking metformin and why that drug is almost always the first ingredient included in "life extension" cocktail drug tests.

Comment · 6 years ago

"...The results suggest that push-up ability might be a simple, reliable and D.I.Y.-in-your-living-room method of assessing heart health..."

I call BS. Body weight exercises like push-ups are more difficult for taller people.

<sarcasm>A a better predictor of heart health might be how quickly you can clean the top of the refrigerator. </sarcasm>

Comment · 6 years ago

carapace says>"Little rings of gunpowder in the paper to make it act like a fuse..."

There is no gunpowder in cigarettes:

https://www.verywellmind.com/big-tobaccos-list-of-599-cigare...

https://boards.straightdope.com/sdmb/showthread.php?t=27857

A non-addictive cigarette would have to have no nicotine b/c nicotine is addictive:

https://www.drugabuse.gov/publications/research-reports/toba...

"Source: A long time back a friend of mine's brother was part of a faux-jury assembled by tobacco company lawyers to do like a focus group to research how real juries in some real trial might think/feel."