jstandard

Non-hardware person here. How does the D1 compare to Cerebras WSE-2 wafer chip with 2.6 trillion transistors?

The WSE2 is much larger obviously, but I would also think it can result in a large performance boost given everything is on a single chip.

I call it "disruption management". A strong assistant knows your priorities, often times better than you when you're being bombarded. They help manage the firehose of requests, logistics, details, and information to keep you focused on what's important.

I appreciate what Tim has done and continues to accomplish to raise the profile and acceptance of startups as a viable career choice in Japan.

I've first-hand experience with the many challenges of startups in Japan. Finding talent who understand how startups are different. Convincing larger partners you're not simply another "supplier" they can grind margin out of. Explaining to potential investors the tradeoffs of quality, speed, and confirming product fit.

Educational platforms like what Tim has built through podcasting are needed to help close these gaps.

Thanks to Tim for the insightful post on "how the sausage was made" and looking forward to seeing good things coming out of Tepco's innovation platform.

A friend of mine is the head painter at Chilton San Carlos. He said the volume there currently is absolutely insane as the Model 3 has ramped.

They are swimming in wrecked or poorly put together Model S/3s.

His accounts match the tone of the article, though Chilton experiences it to a lesser extent since they're so close to the Tesla mothership.

Where can I find information about the potential requirement for evacuation within a 150+ mile radius? I didn't downvote, just interested in learning more.

What is your criteria for size of fish? Enron's market cap was $60 Billion.

I see your point. The admonishment to Sahil at the end to "stop using" the term "lifestyle business" does seem to miss Sahil's self-awareness of the internal conflict between knowing about the misuse of the term and yet still allowing it to affect him at one point in time.

It's refreshing to see this perspective from founders. It's a story not often told and does well to characterize the grinding rollercoaster of hard decisions you won't easily find in the sea of "A-co raised $40mm!" press releases.

Agree the essay was a great read. I didn't see anything to suggest the OP missed that fact so much as had a reaction to a specific part of the essay and wished to discuss it.

Being a part of the SV startup ecosystem myself, I also see the term "lifestyle business" used as a soft-perjorative for "not ambitious enough".

Thanks, the overall explanation makes sense now.

> The technology 23andMe uses is wrong about 1/10,000 times

Is 23andMe's tech considered state-of-the-art? I'm assuming there are ways to reduce both the false positive and false negative rate and I'm curious how other labs/tech stack up against these rates.

Thanks, this is fascinating.

How is error rate being defined in this case?

I took your explanation to mean: Cancer is common, so the genetic blueprint for Cancer risk factors should also be common. We have a higher number of samples to verify against which increases the detection accuracy.

For less common diseases, we have a smaller pool to verify against, so our blueprint is less accurate. Lower detection accuracy.