dasmoth
Joined 16 years ago
Joined 16 years ago
Clearly, if you are fairly consistently sticking to 2-minutes showers, that's going to be more economical than baths -- even with some degree of sharing.
If you have a family, can you share a bath (taking turns)? That's a substantial and fairly easily-achieved saving.
If you've got a garden, adding a gray-water collection system also makes things that little bit less wasteful, at least in the summer (but I suppose that would also work with a shower too...)
There’s quite a lot of pre-Cisco history in this paper: https://www.cs.indiana.edu/~dyb/pubs/hocs.pdf
Those mutation descriptions are called HGVS (Human Genome Variation Society) nomenclature. In the example you give, "c." means that it's in a (protein) coding region, 345 is the position within the region, and G>E would be the change (although E isn't a valid "letter" in DNA sequence, even if you allow ambiguity codes -- you'd normally see something like G>T there instead).
Complications include:
1) You need to know which gene this is relative to.
2) The "coding sequence" for the gene isn't always perfectly defined, due to splice variation and different versions of the annotation. Ideally, you'd see this code relative to a specific splice variant (which might have an ENST identifier, from http://www.ensembl.org/). But it depends...
More at http://varnomen.hgvs.org/ if you're curious.
https://steveblank.com/2009/12/21/the-elves-leave-middle-ear...
(Slightly startled to learn that was published nearly a decade ago!)
https://tad.me.uk/