chrisprobert
Joined 12 years ago
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http://chrisprobert.com
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Comment · 7 years ago
insitro | Machine Learning for Drug Discovery | South San Francisco, CA | Full Time | Onsite
insitro is reinventing drug discovery by bringing cutting-edge machine learning in a closed loop with our high throughput robotic biology data factory.
Current software roles include:
- Machine Learning Engineer
- Data Engineer
- Head of Data Engineering
See: http://insitro.com/jobs or feel free to email me: [email protected]
Comment · 8 years ago
I'm curious whether this is backed by Google File System (https://static.googleusercontent.com/media/research.google.c...), or something else.
Comment · 8 years ago
What's interesting about this approach (TIL expansion) relative to other leading cellular immunotherapy approaches (CAR-T/NK and TCR) is that it doesn't rely on gene editing. Long term, I think genetically "programmable" cellular immunotherapies are more likely to win (e.g. because they can be programmed to overcome tumor immune suppression), but it's impressive that a durable response is achieved here with clonally expanded TILs.
There is a great review on progress in cell based immunotherapies here: https://www.cell.com/cell/abstract/S0092-8674(17)30064-8
Comment · 8 years ago
Coupa Cafe on Ramona St. in Palo Alto, or the one in Y2E2 at Stanford.
Comment · 9 years ago
Totally agree!
Comment · 9 years ago
Announcing TensorFlow's new development roadmap mandate: copy everything PyTorch is doing :-)
Comment · 9 years ago
Great to see this coming from a team with such a solid AI background!
Comment · 11 years ago
I would put > 50/50 odds on there being a human alive today with at least one CRISPR-edited germline variant. I think the question is now how can we regulate/control CRISPR germline editing; not how can we prevent it.
Human embryo gene editing was reported in May 2015 (http://dx.doi.org/10.1007/s13238-015-0153-5). It's reasonable to assume that the editing took place significantly before the submission date, especially given reports that the paper was first rejected from several other journals on ethical grounds (http://www.nature.com/news/chinese-scientists-genetically-mo...). I'm not trying to suggest that these particular scientists have performed experiments on viable embryos also, but I'd be very surprised if someone hasn't.