chaimanmeow
Joined 5 years ago
Joined 5 years ago
This might need major fix
> In a 64-bit ISA, each instruction is represented using 64 bits (8 bytes).
Not as I understand it and maybe only for exotic ISAs like VLIW. For most other, CISC or RISC, I think the instruction length might be much smaller, and in some cases, x86 for example, the length of instructions is variable (one of the reasons they have a decoder). The size of the registers is 64 bits, as are the ALU operations on these registers, and the length of the words that are addressed in memory.
Molnupiravir promotes G to A mutations as well as to a lesser extent, C to T mutations
The authors conclude "Overall in the dataset, we observe a systematic accelerated evolutionary rate in high G-to-A branches (p<0.001), consistent with the action of a mutagenic drug."
https://www.medrxiv.org/content/10.1101/2023.01.26.23284998v...