brinedew
Joined 10 months ago
Joined 10 months ago
> I wonder if there's a way to ease the difficulty by filling in 'correct' features of the guesses
Rather than allowing players to guess individual features, I opted for the "highlight" system where all hidden features that match your guessed protein's features get auto-revealed. This way, if you suspect a transmembrane protein, you can just guess a known transmembrane protein and see which features auto-reveal.
> it would have been interesting to sift through classes or cell types
You're welcome to suggest databases with good coverage over the proteome that I could use for these.
> I presume you're showing even the 'low confidence' portions of the predicted structure?
Yes, any residues in the files I fetch get rendered. I rank by coverage before fetching.
> You could also show the primary amino acid sequence too
I'll consider it.
Making a nice-looking web GUI without knowing relevant vocabulary was a very clunky process in comparison to code pipelines, basically just pasting screenshots into the chat window and asking LLMs to "line up stuff properly", which they still couldn't manage to do in places.
There's almost 20k entries in my human gene database. You can choose any of them as your guess, but the "gene of the day" is chosen from a subset that has decent 3D structure coverage (meaning, not falling back to alphafold2 for visualization).
If you're interested to learn more about proteins, I suggest asking an in-browser LLM like Claude Chrome to play and explain its guesses at your preferred level of familiarity. https://claude.com/chrome