88e282102ae2e5b

Joined 12 years ago

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Comment · 8 years ago
Ah, I see, thanks. Still, that's a non-starter. Many of the packages I use are not available through any system package manager, and it would preclude using virtualenvs.

OTOH, I desperately want to move away from Python.

Comment · 8 years ago
The problem is, I am using the package manager (pip in this case). I guess because the wheels aren't built for SmartOS it has to compile them.
Comment · 8 years ago
I really wish I could use SmartOS, but I couldn't even install some common Python packages without getting a compilation error. Looking such problems up on issue trackers revealed old requests for compatibility with SmartOS, and no follow-up from the developers.

I'm not sure what the recourse is, I just don't know enough about C to fix this myself. I assumed this would be a common enough problem that the solution would be well documented somewhere but there seems to be nothing out there even mentioning the issue.

I'm happy to do all my work in LX-branded zones, and that's certainly better than the alternatives (for my purposes), but having two operating systems still kinda irks me.

Comment · 8 years ago
Biophysics and biochemistry would both fit the bill.

I would not take the site you linked seriously - it's the ramblings of a crackpot. If you happen to have a biology background and would like to debate this, I'd be happy to elaborate.

Comment · 8 years ago
Is there anything more to it than carving a piece of silica and ligating the adapters to the surface? I mean, I know the process is a bit more involved than that but the patents make it seem relatively straightforward.
Comment · 8 years ago
This is a huge red flag for me. Maybe if you made your own bootleg flow cells and reagents? But even that seems like a stretch.
Comment · 8 years ago
That's fair, my generalization was pejorative. I meant to say, in a glib way, that this is not a website frequented by 100% licensed physicians and clinical researchers, and is actually mostly not that.

The point is, the OP is essentially saying, "I wish to discard the notion that statistical research is valid and may make medical decisions based on a study with N=1 or 2". I was worried people would show up and offer magical cures as they always do, and lo and behold, there are threads suggesting hypnosis and turmeric.

My main concern with this is that the OP may use a completely arbitrary "cure" and avoid speaking further to doctors about it, so any actual treatments that are developed might be overlooked.

Comment · 8 years ago
It can also make things actively worse - it's not just additional information, but potentially disinformation.
Comment · 8 years ago
I can't help, but I can guarantee you that getting unlicensed medical advice from web developers won't make things better.
Comment · 8 years ago
Cpf1 is patented, it's just that there's no dispute over who owns it.
Comment · 8 years ago
No. Working around this takes some effort but is straightforward and uses well-known, existing techniques. There's a lab I know of that considered trying to modify the protein so it could evade the immune system, but they decided against it since they figured the group that published this paper would have too much of a head start and there's no way they'd be able to compete. I'd give it a year or so, and that's assuming none of the other Cas9 or Cas12a variants are already usable.
Comment · 8 years ago
I've been happy just dual-booting Windows and Linux. Windows 10 is free as long as you don't care about personalizing it, which I definitely don't, since it's just for games. I look forward to having a Linux-only machine but I'm not in any hurry.
Comment · 8 years ago
Also, consider this from the manager's perspective. They have to ask themselves: if this person has 35 years of experience, they must have a substantial network, so why aren't they just tapping that resource? Not a single person from this applicant's past wants to give them an interview?
Comment · 8 years ago
> So the input for this technology is imaginary.

They proposed one use, which would be to use it as storage for solar/wind power. Perhaps their plan is that when there's excess output from renewables, they'll use electrolysis to generate hydrogen gas from water?

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