Skylines is hands down my favorite game right now and is directly responsible for my highly unproductive, but fun, weekend. But it's not without faults. For me one of the telling things will be how they handle a very similar problem that EA had with the latest Sim City. Traffic. Once your city becomes a certain size the game goes from City Builder to Traffic Management Simulator. Which itself wouldn't be a problem if not for issues with the simulation.
For example if you have a 6-lane, one-way, road with intersections cars will get into the right/left lanes as soon as they get on the road, even if that's on the other side of the map from where they're turning. Causing the middle lanes to become useless and the others to be backed up (admittedly this isn't totally unrealistic though). I remember Sim City had similar problems and I'm sure it's a tough one to solve. Especially on a big game world with hundreds, or thousands, of intersections and tens of thousands of cars being simulated at once. Even if they don't solve it I'll still be burning my weekends on this game for a long time.
For example if you have a 6-lane, one-way, road with intersections cars will get into the right/left lanes as soon as they get on the road, even if that's on the other side of the map from where they're turning. Causing the middle lanes to become useless and the others to be backed up (admittedly this isn't totally unrealistic though). I remember Sim City had similar problems and I'm sure it's a tough one to solve. Especially on a big game world with hundreds, or thousands, of intersections and tens of thousands of cars being simulated at once. Even if they don't solve it I'll still be burning my weekends on this game for a long time.