This reads to me like Victorian fears of buildings over three stories (you'll asphyxiate) or the idea that humans will die instantly when moving faster than a horse could carry you.
I see no reason whatsoever to expect that humans have any kind of limit to what we can understand as a species. We've had more unthinkable and incomprehensible discoveries than anyone cares to count. They become understood, normalized, and folded into our scientific canon. We went from inventing airplanes to landing on the moon in a matter of decades. We went from banging rocks together to quantum physics and string theory. I think we'll be alright.
I see no reason whatsoever to expect that humans have any kind of limit to what we can understand as a species. We've had more unthinkable and incomprehensible discoveries than anyone cares to count. They become understood, normalized, and folded into our scientific canon. We went from inventing airplanes to landing on the moon in a matter of decades. We went from banging rocks together to quantum physics and string theory. I think we'll be alright.