Comment by Fwirt

Space is really, really big. I think it's hard for us to comprehend just how much space is in space, especially in 3-dimensional terms. It would take a lot of sand to mine all of the useful orbital space, and that's just LEO. There's tons of room in higher orbits. It would measurably increase the risk of passing through LEO on the way to other destinations and make some orbital planes unusable for e.g. Starlink or human habitation, but when you're just passing through, the odds of getting punctured are probably still reasonable, at least for unmanned spacecraft. Keep in mind that the ISS maneuvers out of the way when there are several miles to a potential impactor, just in case. We have all our eggs in one basket right now, so everybody is really careful with that one basket.