Apparently I'm the only one here who finds it to be one of the worst things I ever have to do, I hate managing the combinatorial tab explosion by hand. Compounded by the adversarial nature of the price-setting algorithms that jack up the price on you if you show too much interest by researching too intensively. Just booked a flight for our family in two parts, and booking for one set of us made the price for the second set of us with a slightly different itinerary massively more expensive, because it was "in demand".
Can't wait for agents to handle all of it.