Comment Comment by aaauaucuggaa Generally speaking:- Delivery: getting the mRNA and guide RNA into the target cells- Expression: ensuring the target cell expresses the mRNA, thus making the protein- On Target Editing Efficiency: ensuring the intended edit happens at a high rate- Off Target Editing: ensuring other edits in other locations do not occur parent aaauaucuggaa 2 years ago
- Delivery: getting the mRNA and guide RNA into the target cells
- Expression: ensuring the target cell expresses the mRNA, thus making the protein
- On Target Editing Efficiency: ensuring the intended edit happens at a high rate
- Off Target Editing: ensuring other edits in other locations do not occur