I'm using VMs for everything. Disposable, self-destructing VMs for untrusted browsing. Network VM solely for connecting to the Internet, Firewal VM for isolating the network from other parts of my system. Work VM for everything connected to work. Archive VM (with no networking) for storing important files. Banking VM for managing bank accounts. Zoom VM for isolating Zoom from the rest of my system. And so on.
All this works with a great, unified interface on Qubes OS (https://qubes-os.org). See also: https://forum.qubes-os.org/t/how-to-pitch-qubes-os/4499/15.