I've been using web components in production for a while now and it's great. Our front end "stack" consists of a single polyfill and Webpack. Use template literals for templating, so you don't even need handlebars/mustache anymore. Webpack lets you write SASS that is compiled directly to CSS and inserted in your shadow DOM with an ES6 import, so no more style sheets for anything but high level page layout. Everything is standards based web components written in vanilla ES6, transpiled for browser compatibility down to IE10.
One major issue we've had though, which wasn't touched in this article, is inter-component communication among siblings. Sure you can just do a global event bus, and that works, but I've yet to see an elegant solution for this yet.
One major issue we've had though, which wasn't touched in this article, is inter-component communication among siblings. Sure you can just do a global event bus, and that works, but I've yet to see an elegant solution for this yet.