Recent submissions

Comment · 2 days ago
Super weird that the only relationship documented in this article is two "dinners with AI executives in Asia." Does that count as a close relationship? I get invited to AI dinners in the Bay Area nonstop, and I understand they are always transactional (people wanting to sell me stuff), not actual relations with people who just happen to enjoy my presence...
Comment · 3 days ago
This includes only diagnosed cases of colon cancer, so if India has much less screening and fewer diagnostic opportunities, that will greatly reduce its score. But it is still a striking number!!
Comment · 3 days ago
Important context in the article:

"The data showed that the age-adjusted incidence rate fell from 55.2 per 100,000 in 2000 to 36.7 in 2022, then rose to 38.3 in 2023."

If you would like to advance a theory that this is because of a specific environmental change, your theory should cope with the fact that the rate was MUCH higher in 2000 and the rise described here is is 2023. Increased screening is said to be a likely culprit in this case for middle-aged adult prevalence but not for older adult prevalence, because screening has increased somewhat in the middle aged groups.

I am personally dealing with colon cancer, and one of the incredibly annoying things about the awful disease is the number of truly clueless people who use it to advance some culinary agenda they believe in without evidence.

Comment · 5 days ago
Comment · 6 days ago
Amazingly, when this (IMHO quite good) data leaked, Moderna stock took a huge drop: https://finance.yahoo.com/markets/stocks/article/moderna-sto... (Seems like people were expecting absolutely incredible, "cure for cancer" results and had already bid up the price a lot in advance.)
Comment · 9 days ago
Does anyone know what is happening to the company eMudhra? Are they being sued into oblivion? Taken over by Indian government? Or just doing business still?
Comment · 12 days ago
I'm not at all anti-AI, but I'm still holding my breath to see real scientific contributions coming from modern (LLM/CoT/agent) AI. Much of the premise behind "AI will make superabundance a reality" hinges on getting AI-driven science that affects everyday lives Anthropic's quasi-CRISPR-like discovery did not seem super compelling, and that is still the best I have seen. If anyone has more heartening stories that could convince me to be an optimist, please do share ;)
Comment · 13 days ago
It’s such a good movie. Go with a friend and you can spend hours picking apart the layers.
Comment · 17 days ago
As a fellow cancer-haver, I would give a piece of proactive advice for those (in the US) who do NOT have cancer or even suspect they have it:

Find a decent primary care doc who is not impossible to schedule with. Someday, if you do have a problem, the primary care doc will be able to send you off for scans, etc. much more easily when you are an existing patient. Getting appointments as an existing patient is much easier.

Comment · 19 days ago
I'm ready to blame the current admin, federal funding cuts, and cuts to immigration, but we all do need to check that the year for this change is clearly 2024... (But I am also ready to be even more depressed by 2025 stats!)
Comment · 1 month ago
Ok, but how do the economics of this work? Based on its settlement, Anthropic paid an average of $3000 per work they scanned based on their settlement (https://tech-insider.org/au/anthropic-copyright-settlement-2...). They and OpenAI pay billions per year for a mix of experts and normal people to label or create data. Why would they continue doing this if the value of this is immediately copied by open models? If your goal is to end the economics of generating and buying data for AI (and I recognize for some people this is really the goal) then sure, but if you want AI for various subfields of interest to continue improving then it's not workable.

Back when people made arguments for software privacy, the argument was usually "big business will still pay and consumers wouldn't have paid anyways so it's ok for us to pirate" - I actually think that was fine for business software but terrible for indie games, whose market was 0% businesses.

But in the AI case, it's not like they get to keep some of the value of their investment - it all gets cloned into models that businesses and consumers alike are happy to use. If someone knows how labs could continue to fund data creation and acquisition in this model, please do share!

Comment · 2 months ago
I uninstalled basically all of these EXCEPT youtube, and that's what I struggle with sometimes now. I find so much great long- and medium-form content on Youtube that I want to keep it around. But I have to admit that I can sometimes fall down a time-wasting rabbit hole with shorts.

The Youtube app now has a "shorts feed limit" under "time management" that will limit your access to the auto-scroll shorts feed to a certain amount per day. Worth checking out!

Comment · 2 months ago
I'm a good target market for pro-coffee writing, but this is just an observational study of a drinks habit. No one in the general public should have any interest in studies of this kind.

Maybe if you're deep in working in this research space it could help generate hypotheses for more meaningful research? But "we cross sectionally compared two groups with different behaviors and found they were different" is not really a result.

Comment · 2 months ago
The NYT just did a story on Andon: https://www.nytimes.com/2026/08/04/us/ai-boss-san-francisco-...

Their AI "boss" appears to be pathologically chill and worker-friendly. Has never denied a request for a day off.

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