ub-volta-toss

I did this a few times and found it miraculous. The doses were sub k-hole, it just made the world seem cottony and soft. The effect on my psyche was lasting and positive.

A friend who struggles with depression found it useful for a while, but its effects didn't continue after a number of doses.

Do you have a list of common red flags that engineers should avoid when considering working at a startup?

See above. Its not so straightforward. You need enough headroom on each component that a negative feedback loop can start, eat resources, and have enough time and resources to calm itself before hitting some limit or degrading itself further

Nope. They hit the scale limit with Cassandra and now have an in-house storage layer

I'm not sure how Uber does it, but it might be because they're using Cadence instead.

The Temporal team has acknowledged that Cassandra-backed Temporal hits scaling limits pretty fast.

The limitations aren't a clean "X actions/sec", they're sneakier. Because you can run X/sec for days and then the memory on the history service will spike, or any tiny slowdown in the DB will cause looping degradation. There are nasty feedback loops hidden in Temporal that turn small problems into very very large problems.

I think the core problem with Temporal is the way its sharded. This affects history service and its caches. If anything tells them to reload or restart, or that any of the nodes are unreachable, you get a retry storm on the DB.

In addition to these issues, Temporal can create feedback loops within itself. I've seen cases where it would not return to health, even with 0 workers requesting work for 10s of minutes.

We could have kept using and scaling Temporal, but it required 10-30x the resources of building something else. And it was scary to administer. You really need an entire team. You can't have somebody who isn't a dedicated engineer take on-call for it.

Temporal is really neat but I think its marketed at too many use cases.

After a year of high-scale Temporal work, I found it was only good for low-scale work.

The onboarding and learning curve were insanely difficult and complex. Ultimately it doesn't scale as well as you think. The temporal team invented their own database to get around this limitation.

Employee reviews are a very underrated way to judge a company. Especially one that offers breakthrough tech

Further reflection- this video is a little sketchy. it has subtle flaws that look like red flags

- Nobody who works in a lab would call screw cap tubes 'these little tubes'

- Shows no action from machine

- How is machine supposed to open 'these little tubes'? It can't unscrew them.

- If the operator starts the machine with open screw-cap tubes (usually full of expensive things) how would the operator (or robot) close the tube for the rest of the run? Leaving it open is bad, seems like opening the machine should be bad...

I think if this company actually had a working machine, they'd show it working

edit: glassdoor reviews are insaaaane. if people are willing to leave reviews like that at a company this small, its gotta be worse than they're even describing.

so much promise in the bio space absorbing tech, so much peril when tech tries to bio

that vimeo is just a guy talking? lets see some science!

i think nato built something like this at uBiome, but it never saw use. another yc that scrubbed the glass-door reviews