tdido

Joined 6 years ago

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Sep 9

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Comment · 3 days ago

CNIO is one of Europe's leading cancer research centres. We're hiring a systems administrator to run the infrastructure behind our research: petabyte-scale storage, backup and archive (including tape), Linux and Windows servers, and AD/M365 accounts. You'll work alongside senior colleagues, with room to take ownership of core systems as you grow.

What we're looking for:

- 3+ years of hands-on Linux and Windows server administration (not desktop support), including AD and file-share permissions

- Experience with enterprise storage or backup/restore

- Scripting (Bash, Python, PowerShell)

- Someone who cares that restores actually work

- Bonus: large-scale storage, tape and archiving, M365, virtualisation, config management, ENS or ISO 27001

- English and Spanish at professional working level

Apply by 11 November: https://www.cnio.es/empleo/systems-administrator-infrastruct...

Informal enquiries: tdidomenico-at-cnio-dot-es

Comment · 2 months ago

Spanish National Cancer Research Centre (CNIO) | Madrid, Spain | HYBRID | Senior Scientific Computing Engineer | Full-time

CNIO is one of Europe's leading cancer research centres. We're looking for a senior scientific computing engineer to join the IT, Scientific Computing and AI area and take ownership of the infrastructure behind our research, from genomics pipelines to AI models. You'll be the senior scientific computing person in the area, reporting directly to me (the area head), and you'll help define where scientific computing at CNIO goes over the next few years.

What you'll do:

- Shape the roadmap for scientific computing at the centre and drive it forward

- Own and evolve our HPC cluster (Slurm): scheduling, monitoring, capacity planning, user support

- Build out our GPU / AI infrastructure as the centre's ML workloads grow

- Work with researchers to turn their analyses into robust, reproducible pipelines and tools

- Optional: co-author research papers

What we're looking for:

- Several years running Linux HPC environments in production (Slurm or similar)

- Comfortable with automation (Ansible, Python), containers (Apptainer/Docker) and workflow managers (Nextflow, Snakemake or similar)

- Someone who wants to set direction, not just keep the lights on

- Bonus: Ceph, Kubernetes, GPU stacks, a bioinformatics background

- Spanish not required

If interested: tdidomenico-at-cnio-dot-es.

Comment · 6 months ago

You can go a very long way just mapping your DNA reads to a reference genome [0]. This reference will have associated annotations of different types, e.g. mutations, which automatically give you relevant information about your own genome by being present in it (or not).

Mapping is a fairly straightforward process where SOTA software is FOSS (as is most bioinformatics software). Accessing databases can be as simple as linking your data to the UCSC genome browser [1]. Of course, if you want to go the manual way, the sky is the limit.

[0] https://www.gencodegenes.org/human/

[1] https://genome.ucsc.edu/

Comment · 1 year ago

See here for updates: https://bsky.app/profile/matrix.org/post/3lxuslbzjuc2t

Comment · 1 year ago

That's actually pretty much what Andrej Karpathy mentions as a mitigation for hallucinations here:

https://m.youtube.com/watch?v=7xTGNNLPyMI&t=5400s

Comment · 1 year ago

Spanish National Cancer Research Centre (CNIO) | Madrid, Spain | HYBRID (2d/week on-site) | HPC Engineer | Full-time

We're looking for an HPC engineer to join us at the Bioinformatics Unit to help us boost the scientific computing infrastructure at our research centre.

What you'll do:

• Administer & grow our HPC cluster (Slurm)

• Help implement our new storage system (Ceph)

• Optional: write tools and/or co-author research papers