Recent submissions

Comment · 6 years ago
Comment · 6 years ago
But peroxide is not just some random thing like bleach. It's generated internally from superoxide dismutase in the normal process of scavenging radicals and is also an immune signalling mechanism. As mentioned, it is reduced by a reaction catalyzed by peroxidase so the body "knows" how to shunt it around safely and reduce it when necessary. It's perfectly safe in appropriate dilution on scrapes, cuts etc. The key is not to overwhelm the antioxidant defenses. Lung tissue is much more delicate, but it's not ridiculous to suggest that a very low concentration might be worth testing.
Comment · 6 years ago
Peroxide is directly virucidal through oxidation of the lipid envelope and RNA degradation. Whether lymphocytes would be activated in lung tissue in vivo is entirely speculative.
Comment · 6 years ago
The dose makes the poison.
Comment · 6 years ago
There are also those proponents of nebulizing (dilute) peroxide. While I wouldn't try this myself, peroxide modulates lymphocytes and would surely result in a decrease in viral load. Peroxide is not unknown to the body, given the various endogenous peroxidases that catalyze it. Dilution would seem to be critical, though. I have wondered whether it wasn't worth some controlled studies, if they haven't happened already (shrug)
Comment · 7 years ago
Comment · 7 years ago
Comment · 7 years ago
It's undoubtedly aimed at musical audio generation and signal processing. A quick search will reveal the number of gotchas in implementing even a simple alias-free (bandlimited interpolation) digital sawtooth wave, never mind arbitrary wave tables. The rebirth of analog audio synths was partially driven by the complex behaviors of real analog circuitry - particularly when you account for saturation, hysteresis and other "imperfections" that don't occur naturally in a digital simulation.
Comment · 7 years ago
I am becoming tired of the word "curated" unless it is being used in a context implying a qualified curator. This could be someone's random list of browser links for all I know. Who are the curators of this list and how are they qualified for me to are about their "curated" list? I don't necessarily mean formal qualifications. Also, curation implies active and personal involvement (as opposed to passive analysis based on statistical measures of relevance or citations). Why in this case would I prefer personal curation?
Comment · 7 years ago
The wispy, near transparent spectacles in some of them are a bit of a give away...
Comment · 7 years ago
I wonder how many of those who run for public office would willingly present results of such a scan... I would bet money that that particular demographic would show an interesting trend.
Comment · 7 years ago
The correct way to counter disinformation is with information. This does assume a sufficiently aware populace able to process its own confirmation bias (which is actually a learnable skill). Sometimes it takes incrementally more information and that's okay.

Widespread availability of high quality media capture and technologies such as facial manipulation will inevitably lead to a future with many, many unverifiable snippets that go viral. This video is unique in that verification is possible, but the future will likely hold far more unverifiable content than otherwise. It is more positive to expect that humans will gain the ability to balance disinformation in the face of further information than to expect that benign dictators will censor perfect knowledge into cognisance.

Comment · 7 years ago
I have taken several CDs (mainly my Dad's, not my own) from unusably scratched to relatively pristine. The really bad cases need fine grit sandpaper (wet!) followed by plastic polishes. I generally start with Meguiar's plastic polish and work my way to Radtech Ice Creme. In my own collection I have CDs that are around 30 years old and are error-free. I'm not interested in formats or services that won't last at least as long or can't be backed up to my own NAS (nor am I interested in anything less than Red Book quality).
Comment · 7 years ago
Comment · 7 years ago
The cynical answer is that sleep medications (and I mean the more highly scheduled varieties) are among the biggest pharmacological money spinners. Melatonin is cheap and unpatentable (although there was several attempts at melatonin mimetics, e.g. agomelatine). It's unfathomable that melatonin is available only on prescription (and has become increasingly hard to obtain). I think the toxicity is close to water... one would be more likely to gag on the number of pills necessary to O.D. and I'm not sure if there's even a single melatonin related death on record.

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