subrat_rout

Joined 14 years ago

Karma
195
Submissions
166
Member since
May 22
HTML5, CSS3, JavaScript, NodeJS, MySQL, PostgreSQL, MongoDB and Ruby on Rails. Previous experience in Healthcare, Microbiology and Drug discovery, Regulatory affairs and now doing software programming especially full stack web development. subratrout.com subrat2040<at>gmail<dot>com
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Recent submissions

Comment · 3 years ago
Mind disclosing the name of retreat and place where one can attend?
Comment · 3 years ago
If Sweden pays $115/day then it comes about $575/week. And if US pays $145/week how it is 30% more than Sweden?
Comment · 3 years ago
One more suggestion. Never ever search any domain you want to buy on GoDaddy. If you search something and the domain name is available and you did not buy it, then good luck getting that domain at a normal price in the future. GoDaddy generally buys it and then parks it with asking price of x100 to x1000 range.
Comment · 4 years ago
How are you taking it? And what does it cost?
Comment · 4 years ago
That was also my initial thought. I thought it would be similar to Heroku or Hatchbox. But I see there are lots of information missing on how to deploy a Rails or Django app with databases and redis etc.
Comment · 4 years ago
It all depends on your level of risk tolerance. Would you want to play safe where you do not want to loose money at all? Invest in inflation protected Treasury bonds. Currently I-bond is paying 7% return.

Would you want to play risky where you do not mind loosing a chunk of the size? Invest in a few obscured cryptos after doing some due diligence where there is a chance of 10-100x return.

Want to play safe where moderate risk is tolerable? Invest in real-estate but it also depends on market and country. People think buying a franchise will make them an entrepreneur but remember franchise is nothing but a job disguised under thin veil of entrepreneurship. In Franchise business, someone else has a major control over your business and you have to play by their playbook rule. In addition, there is a very little room to scale.

However, if you are person with some developer or marketeer skill then this is the best route to go. If you have few ideas then you can test those by developing a prototype and putting in hand of customers and getting feedback. But be aware that for each prototype you should not spend more than 5-10k. If you have sufficient time in your hand then other non conventional investments can be buying farm lands and trying organic farming, providing micro-loans to entrepreneurs etc.

Comment · 5 years ago
How do you buy shares in the SPAC? Is there a minimum amount? Which platform can I use to buy shares in the SPAC?
Comment · 5 years ago
Comment · 5 years ago
I'd suggest go for the tech stack with which you are the most familiar with.
Comment · 5 years ago
Agree. Big name and celebrities should held social media accountable and companies or organizations defrauding people should not get away with these kind of shenanigans.
Comment · 5 years ago
Is Chamath aware of this? Why he is not putting a public statement or warning on this? Is he really giving away all those bitcoins?
Comment · 5 years ago
Ok great to know. But my intention here is to convey that it is dangerous to biohacking a molecule/compound that a user is going to put in his/her body. The peptides after synthesis needs to be rigorously tested(QC/QA) for the desired sequences and to make sure the absence of any undesired epiotopes mixed.
Comment · 5 years ago
I completely agree with fabian2k. It's incredibly risky to throw all random sequences peptides into the blood stream for evoking immune response. What happens if a sub-sequence of peptide matches with one of our own's body proteins and our immune system starts building antibody against it? That's what happens in most of autoimmune disease.

In addition, most of the peptides that can be synthesized from a protein structures are sequential epitopes. To ELI5, imagine a string with beads that starts with A-Z letters and we take a smaller sequence A-B-C-D or B-C-D-E and throw to system to build antibody against it. Yes, the immune system can make antibodies against it. But in real life, most of the protective or virus neutralizing antibodies comes from conformational epitopes. Imagine when the protein gets folded to its natural form then the beads with letter sequences are just jumbled sequences and finding a conformational epitope is key to raise neutralizing antibodies. That is only possible when a protein's structure is fully understood using x-ray crystallography. The article does not disclose how the author was able to get those sequences and how he was sure about its efficacy.

However, the author's bold step towards the experiment is praiseworthy. But extreme caution is needs to be taken as self administering an untested drug or vaccine may fall within the boundary of law and it can invoke regulatory actions against him.

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