Recent submissions

Comment · 2 years ago
This is great. Glad to be wrong.
Comment · 2 years ago
I imagine poetry as an often misanthropic and lonely hobby with virtually zero demand for it’s output. Whether written or spoken. Moreso now there are LLMs.

If I die unrespected and socially isolated I like the thought of donating my body to medicine while providing a funeral for poets to crash and get their words out. It is an absurd concept, it would be nice if they connected socially before I died and provided the respect they are concerned about. But given the constraints of their own lives it is nice knowing my lonely death could provide social support to probably introverted intelligent thoughtful people who are likely at risk of social isolation themself.

What is the purpose of a funeral is an interesting question. I think it is to help the living to socialise and forge ahead with a cohesive story of the deceased ‘s contribution to their own lives and to navigate the gap and hierarchy left in the modified social network. I’m guessing this process reduces grief and conflict as people feel loved and supported through the process.

If you die alone you leave no gap. I think it’s brilliant that Poets seized this opportunity to get a reading in and strengthen their own social network. They are also attributing value and respect to life, no matter how meaningless, which is another positive. The futility and absurdity of the human condition is a beautiful thing we all wrestle with whether socially connected or not and I think this is the point they are getting across while having someone listen to their poetry.

Comment · 2 years ago
May I ask what a non-technical founder should look for in a technical co-founder?

I have two customers for slightly different businesses. The deals are made, I am building MVP's myself and JVing with established tech companies to get products to market.

I have a supply chain with a 30% cost advantage with customers.

and

I have a hardware software system that significantly improves hire businesses that has customers and development partnerships with research organisations and funding applications in progress.

Both have customers and large B2B growth potential.

I am building the MVP's myself while selling and JVing as necessary but would happily partner equally with a technical expert in Microsoft365 and PostgreSQL and PostGIS.

I'm an expert in business design and love technology without being talented or experienced building it. Someone with a business mind and opinions plus the technical skills to build an MVP and hire a technology team would be perfect. I can license my way to market but it will a clunkier more painful start. If I could work with someone who has deep experience with making microsoft365 work smoothly, for small volumes of data and a small number of users initially, then they would add value to both businesses instantly.

My question is should I grind through this myself with JV's where needed using architects on contract for the tricky bits and build the technical knowledge to be a really good technical work partner enabling recruitment of a better technical co-founder or should I recruit the best technical-cofounder I can and get on with growing the businesses.

I would happily take a smaller salary from cashflow than a technical co-founder initially, recognising their market value remuneration as soon as the business is able - likely early year 2. I would even consider technical guidance/mentoring for some equity if someone was interested.

And I know you are supposed to focus on one thing at a time but the software for the two business systems is similar, and I have systems and people to drive the sales and management for both so will offering a technical-co founder 2 bites at 2 potential rapid growth businesses make them think they were increasing or reducing their odds of success?

What questions would I ask to make sure the partnership will be enjoyable for the technical co-founder?

Are there any books/experts on keeping technical co-founders happy?

Comment · 3 years ago
I gradually figured out what activities, supplements and foods reduced my susceptibility to fatigue and pain and then repetitively used them until I got to a point that I was no longer susceptible to fatigue within the bounds of what I consider a healthy fulfilling life so that I can now convincingly pretend to myself that I don't have cfs. I'm no longer staring into the abyss. I can't run a marathon or do too much mental grunt work but I can just make a modest living, go for a 40 minute zone2 run or 3 hour hike, be a parent, sustain a relationship and keep some friendships going. In the midst of cfs I could only really be a part time parent with support, everything else stopped and I had no certainty that it would ever start again.
Comment · 3 years ago
And after writing that I realised strength training is one of the recovery shortcuts for pacing. Smart people probably read this and think Doh, I'd be fatigued if I had that guy's problem solving ability.

There are plenty of other shortcuts.

I think this is the gist of what I'm whinging about regarding CFS treatment options.

More people would recover faster if Mindfullness wasn't the only tool available to shorten the process of pacing one's self to recovery. Being chill and treading carefully will work for less debilitated people. The really debilitated people are sensibly avoiding exertion, they aren't signing up for an underresourced olympic swim team .

Comment · 3 years ago
Here's a simplification (that I experienced before I dealt with cfs) -

there is long series of stairways up a large hill that people run up.

You can run up the hill slowly every 5th day without it killing you, then every 4th,3rd 2nd then everyday. That process might take 4-6 months and takes grit.

Or you can strength train your legs with barbell squats once a a week for 8 weeks noticing yourself getting stronger each week and then just run up the hill.

I accept I'm a terrible athlete now so I strength train my legs with very amateurish pistol squats so I can walk up the hill without crossing over the lactate threshold.

If you are crossing the lactate threshold lifting a kettle then strength training should help. I know the exact feeling you are describing and used to deal with it. Gradual strengthening helped - with a strong emphasis on the gradual. Aim for fragmented single limb swimmers stretches. I still remember the pure exhaustion after doing 1 rep. Make sure your body has glucose before after and during any form of exertion. The steadier the glucose flow the better. Getting up and down off the floor is a form of strength training.

There's a balance between strength and endurance and I don't have the explanation off the top of my head but exercise physioloogists do.

Zone 2 exercise heals mitochondria. Zone 3 exercise stresses it and requires a recovery period. Exercise physiologists are having good success treating cfs as athletes are really just optimising their mitochondria so they can thrash it harder and longer than their competitors on race day. Exercise physiologists often work in with physio teams at sports academies at univerisities.

Dr Peter Attias stuff he is figuring out and sharing from helping wealthy intelligent people live long debilitation free lives is very useful for understanding lactate thresholds.

Just like athletes take performance enhancing drugs to reduce recovery times - so can we. There are plenty of supplements to play around with. So many people mess up their B vitamins by taking multi-vitamins but getting b vitamins in quanties your body is utilising is a low hanging fruit. Unfortunately it has no profit motive attached to it so you have to guess or work with a Complementary Medicine MD if you can afford one. A low inflammation, glucose goddess style diet with moderate cheating in the mix so you don't get food obsessed as the base helps also.

The supplement reccommendation page on www.perfecthealthdiet.com is a safe base to play around from for supplementation. If you adapt a soft version of the perfect health base diet to the glucose goddess method and gradually strength train I think you must increase the probability of escaping the fatigue trap. Some of it is mental but if you can get small wins you eventually beat the mental side back as well. Dopamine managment is a factor.

My frustration with some medical professions take is that they sometimes expect you to deal with it purely via mental resilience (which helps) without providing any tools to get any small wins which is impossible. If you think about it - an olympic athlete has a coaching team to ascend mount everest, what do we have?

The medical system treats the condition like someone's on a cave dive and provides the support encouragement, training and advice afforded Eric the eel. They are right that you can do it, panick won't help and that you do need to keep moving in some direction but until you run out of air you will be alright. The fact you can't work is irrelevant, lot's of people deal with debilitation. From the health systems perspective maybe they are right - who deserves saving vs who deserves training are different questions. There is alot of suffering out there - maybe placing the onus on the individual to figure their own path is the correct approach.

Comment · 3 years ago
If you ask great questions you get great answers.
Comment · 3 years ago
Thank you.

I would use fitbits with daily step count, sleep duration and heart rate variability and breaths per minute and resting heartrate and body temperature to monitor patient progress.

I can ask the questions that would partition the useful dopplegangers. If you ask great questions you get the great answers. Then you just need to group the data intelligently.

What I can’t do is be a machine learning expert and database/sys admin and front end developer and negotiator with a public health system.

I’d let the patients vote on their next steps initially. I’d also have psych questionaires to measure their personalities. That would form part of the sympton /genetics doppleganger groupings. As would genetic profiles.

For CFS there aren’t that many logical next best steps. Most things have been tried, there is a sensible order to try things.

This is the case with most chronic illnesses.

However subsets within cfs are better off trying certain treatments before others.

The better a subset responds to a next treatment then the tighter the coupling of their doppleganger to that treatment. Then when any new people match that doppleganger you can reccomend they try that treatment. You’d shift there next best treatment orders around.

As you get more and more data the treatment recommendations get more and more granular and effective.

I could hire a naturopathic md to assign the treatment steps initially.

If anyone wants to do a start up - reach out, I can find funding. Just need a team. I’m going to do it.

I appreciate you sharing your knowledge. But I think you’re assessment of the situation is wrong. I think the general consensus is wrong and I have enough energy now to fafo. Given what I feel I know it feels immoral not to.

Comment · 3 years ago
My point is the franchisees also profit from selling less ice cream provided they don’t lose the trust of their customers.
Comment · 3 years ago
Yes sorry about that.

Avoidance is a part of healing.

If the body is not healing therapy won’t help it.

Comment · 3 years ago
Could you please explain it’s limitations/constraints for this use case.
Comment · 3 years ago
Totally, interestingly they diagnose the illness with a tilt table in some countries.

I had an inversion table atempting to relieve my thoracic pain at the time of my diagnosis. Which was a diagnosis of exclusion. I was gutted by the chronic diagnosis.

I was lucky that the inversion table allowed me to accept that I had the condition post diagnosis because it definitely triggered fatigue after I’d rest at the tilt angles that trigger fatigue.

The awareness of the tilt test and that delayed fatigue onset were the 2 useful pieces of information I got from the cfs support group I attended 3 times. I accepted my diagnosis quickly as I’d accidentally been doing my own tilt table tests with the inversion table. I also quickly realised that regularly whinging about the condition in a support group of people who accepted that they weren’t going to recover from something that seemed treatable wouldn’t help me.

Comment · 3 years ago
Sorry I misread kettle for kettle bell. But the load is irrelevant.

If you are that weak then start with fragmented swimmers stretches 1 limb at a time. I was in the same situation in 2018 but you do forget once you escape. Just do 1 rep on each limb every second day until you can do two. Or figure out the training periodicity for your body so that you can build up to 30 swimmers stretches. Then add in another exercise.

The feeling of muscular fatigue doesn’t matter - the not overtraining is the important bit.

There’s so many other things to get right also but getting physically stronger will only help. I’d talk with a sports physio first if I was in your situation.

Comment · 3 years ago
The physical problem is bigger than the mental problem. There is an underlying physical problem, it just isn’t understood. Because brain fog and pain are the defining symptons then emotional regulation (which is super important also ) gets overblown.

A convalescant event effectively transforms you into a really terrible athlete with shameful recovery periods.

Being physically injured like spraining an ankle is so mentally fatiguing because the brains autopilot modes get temporarily disrupted. It can’t use all its gpu bandwidth and has to switch on other processes to move about.

Proprioception is important, head stability is important, not aggravating the thoracic and cervical spine when moving is important. The stronger you are the more you can achieve without getting to the point of exertion.

There is alot of emotional management necessary for sure - your brain used to work and now it doesn’t. And it hurts to move.

There is also a lot of biochemical management needed to minimise inflammation.

But without a certain level of physical strength then emotional and biochemical management alone won’t allow you to recover.

And it takes grit (which is hard in the face of hopelessness) to get that physical strength back plus a smart diet and supplementation combined with effective emotional management.

If I didn’t have follinic acid in my recovery steps I probably wouldn’t have recovered. If someone hadn’t gifted me a decent bed I probably wouldn’t have recovered. The bed was to support the thoracic spine so I could sleep.

There is a definite physical component to recovery from cfs and this is poorly researched.

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