phasetransition
Joined 15 years ago
Joined 15 years ago
What finishing process, thickness, overspray, masking requirements does your drawing package specify?
This product is about at the point of DVT in development flow, and therefore would be sent to testing about now. But, instead, being sent to backers.
PS, not a hypothetical circumstance for me. I've previously certified a number of luminaires under UL and CB Scheme. I was the technical chair of ANSI C136.37 for several years, and on the working groups of several other standards.
For this specific application, the manufacturing method determines the porosity of the material, and therefore the heat transfer.
CNC prototype parts will have better heat transfer than pressure die cast, and the pressure die cast will perform better than pressureless cast parts.
PPAP were developed to help tackle this sort of thing in a somewhat uniform way, but vendor diligence can take many other forms, too.
We would like to get him in the 5's, and I believe we'll get there. He was below 6.5% every checkup so far except the most recent one.
Between honeymooning and growth hormones, it's difficult to keep him in range from 10pm to 3am, while also not triggering a low after his stomach is empty.
1. Insulin helps get sugar into cells. Glucagon gets stored sugar out of the liver into the blood. Diabetes management in 2025 only deals with supplying external insulin.
2. There are several variants of diabetes. Type 1 is an autoimmune disorder where the body attacks the cells that make insulin.
3. Too much insulin equals all the sugar getting sucked out of your blood and lymph and into cells. This is really bad in an acute way. Your brain cannot run without sugar. Accidentally give yourself too much insulin for the sugars and wind up dead or in a coma in short order.
4. Highs are also bad, but generally in a less acute way. There are exceptions, but being too high with blood glucose for a period of time doesn't have the acute risks of being too low. Diabetics (or their caregivers) carry around quick absorbing sugar sources to help against a low.
5. The peak action (fastest reduction in blood glucose level) of the common insulin, in the way we dose it, peaks 90 - 120 minutes after the dose. The long tail is about 5 total hours of action from the point of dosing. So you should give insulin in advance of when you expect digestion to move glucose into your bloodstream. This is tricky. Also, as insulin ages, the peak of the action happens later. If a new vial is 90 minutes, an nearly empty vial might be 120 minutes after dosing for peak action.
6. CGMs, the on-body instrument in question here, are both flakey and amazing. There's a novel of good and bad here. I'm glad they exist, they can be cantankerous. They are a tiny potentiostat, if that is something you happen to be familiar with.
7. Very high blood sugar is treated with extra insulin to overcome the osmotic pressure of having too much glucose in the bloodstream. There's also a lot of chemistry here (glycocalyx to get you started). If your blood sugar is high you generally need more insulin to get past the hysteresis effects. Once the blood sugar starts to come down, that extra insulin is still around, and can cause a dramatic low. CGMs let you observe this, and "catch the low" by eating sugar to replenish the baseline sugar trapped in circulation.
8. Diabetes management is challenge every day, multiple times a day. Especially with small child who doesn't communicate to you about what they believe about their blood sugar. This is my personal circumstance.
9. Endocrinologists have suggested some wild stuff to my wife and I. For instance, keep a tube of cake icing around, as you can administer it rectally to a child who is passed out (or worse) from a deep low blood glucose. This is how poor the standard of care can be.
Father of 4.5 YO son with Type 1 diabetes, and materials engineer by education.
We've managed to keep our sons A1C in the 6-7% window after we changed our diet to be heavily carb controlled.
Serious injuries or deaths is a terrible feeling, even if the end result was better safety for the rest of the workers.
I comment in geneal support of this advice.
We have started to submit a presentation that would be used for an examiner interview as our provisional application.
It also has informed family diet change, in the direction of keto practices, that has compressed the baseline to high delta for our son.
It's a relief to know that an OTC product exists as a backstop to our prescription CGMs.
Open ended matters, like probate, starting an IP portfolio, or response to a C&D trigger a retainer.
Practical examples from a US perspective, where the existing customer has a strong anchor for timely delivery:
1. McMaster-Carr couriers tons of stuff to industrial and commercial facilities. Partner with one of their exist carriers.
2. Local automotive repair shops need parts delivered.
3. Durable medical equipment delivery.
4. Overflow capacity on your local contract FedEx routes.
5. Emergency runs for event or wedding planners.
6. Fresh produce, greens, and fish for restaurants.
7. Airport to hotel lost luggage courier.