Recent submissions

Comment · 1 month ago
I work on long horizon scientific tasks with expensive computational tools. In that case users are basically asking for the harness to stop and confirm the cost (and plan) before it goes ahead
Comment · 2 months ago
A proxy?
Comment · 5 months ago
Most people I know underutilize voice mode. Such a game changer for making brain dumps the LLM can just gobble up
Comment · 9 months ago
Curious how HN is using this information to plan your investing approach. Does the typical approach, broad market globally diversified still hold assuming dedollarization?
Comment · 2 years ago
Comment · 2 years ago
TandemAI | Senior Front-End Engineer | HYBRID in New York City | https://tandemai.com

TandemAI is focused on lowering the barrier to entry to the most advanced tools in drug discovery. We designed our fully integrated pre-clinical drug discovery platform to empower researchers to discover therapeutic candidates faster and more efficiently.

What You'll Do: Develop highly specialized drug discovery interfaces. These are data-intensive applications that are highly interactive and allow researchers to launch and analyze simulations right from the browser.

Must-Haves: Fluent in English. Proficiency in React. Some knowledge of Chemistry (i.e. you should know what the difference is between a stereoisomer and a tautomer) Send a message with title "HN Senior Front-End Engineer" to frederick dot parsons at tandemai dot com

Comment · 2 years ago
TandemAI | Senior Front-End Engineer | HYBRID in New York City | https://tandemai.com

TandemAI is focused on lowering the barrier to entry to the most advanced tools in drug discovery. We designed our fully integrated pre-clinical drug discovery platform to empower researchers to discover therapeutic candidates faster and more efficiently.

What You'll Do: Develop highly specialized drug discovery interfaces. These are data-intensive applications that are highly interactive and allow researchers to launch and analyze simulations right from the browser.

Must-Haves: Fluent in English. Proficiency in React. Some knowledge of Chemistry (i.e. you should know what the difference is between a stereoisomer and a tautomer)

Send a message with title "HN Senior Front-End Engineer" to frederick dot parsons at tandemai dot com

Comment · 3 years ago
I'm curious how you are doing multithreaded in the front-end. You're talking about modifying your global state from a web worker?
Comment · 3 years ago
My team is currently using this and I've been wondering if there are reasons to move to something like jotai or Zustand. The ergonomics of react-hooks-global-state with TS is quite nice already.
Comment · 3 years ago
This. Along with a global state library of your choice for everything that is not server related data.
Comment · 3 years ago
TandemAI | Software Engineer | Full-time | NYC/Boston/Remote (US, Canada) | https://tandemai.com/

Tandem AI is an advanced technology company dedicated to reinventing drug discovery infrastructure. The company integrates proprietary AI-driven, high-performance computation with its efficient, large-scale in-house wet lab operations to deliver a turnkey drug discovery solution.

We are looking for a Senior Engineer to join our growing Web Applications team. You will actively contribute to back-end and front-end initiatives for our cutting-edge computational platform with a focus on back-end. The candidate, will work to create a state-of-the-art client-facing molecular design web application that seamlessly integrates the Tandem AI molecular dynamics-based computational platform.

Our stack is React 18, Java Spring Boot, PostgreSQL and we use Slurm to manage our HPC jobs.

If you have a science background and strong engineering skills this could be an exciting opportunity for you!

If you're interested feel free to email me with subject "Hacker News TandemAI" directly at frederick [dot] parsons [at] tandemai [dot] com

Comment · 4 years ago
How would broad index funds with some bond exposure protect against this?
Comment · 4 years ago
Interesting ideas. What does such a portfolio construction look like?
Comment · 4 years ago
So what does the normal working class guy like me do to protect my savings? Currently investing in diversified ETFs doesn't seem to protect me.
Comment · 4 years ago
what is the orange beam in the pictures with the telescope?

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