niekmaas

Joined 17 years ago

Karma
501
Submissions
130
Member since
Oct 13
MD PhD in (computational) pathology and tumor biology. Lifelong geek and programmer. Working on www.summarized.science to make my (and yours?) life easier.
View on Hacker News

Recent submissions

Comment · 2 days ago
"Some of you older programmers may have used jQuery." Oh dear, I'm getting old as the jQuery era was my prime of programming before other activities in life took over. Apparently, as someone in their early fourties I am now in the older category.

On topic: thanks for this great summary of the issue. I too miss the prime stackoverflow days. Although the availability of LLMs has allowed me to learn new things and generate some code again, the passion and love for programming that was on (the early) stackoverflow, I do miss. Also the times of just buying a book to learn about a new tool or language (jQuery in Action teached me a lot) feels different from just asking Claude Code to fix or explain something.

Comment · 4 months ago
Well, that is a statement..! As an MD PhD with over 60 (co-)publications including multiple in top 1% journals I can say for sure that this is untrue. Of course this may be different per topic and country, but there is perfect research being published by non-PhD scientists. In fact, the PI from a top-tier US university I collaborate with for over 10 years doesn't even have a PhD.
Comment · 9 months ago
Well, you're absolutely the target audience. As you can see my focus so far is mostly on (neuro) oncology as this is my domain of interest/work. Let me know if you have any topic requests or have any ideas for additional features to make our lives as medical specialists/researchers easier. Contact form is on the site or just email whatever to the domain (catch-all doing the work).
Comment · 9 months ago
No problem, and thanks for the request! #insulin-resistance is now added: https://www.summarized.science/topics/insulin-resistance/ . I ran it for each month of 2025, if you want to go back further just let me know.

Adding personalised highlights of topics of interest into the monthly emails is my top priority for 2026. Won't be too complicated, just have to set up the right API back-and-forths etc.

Good point about deep dives. I could do that for the topics I'm an expert in, however, by definition, I think this requires domain expertise and is therefore not scalable nor to be automated easily. I'm not sure if this fits the scope of the current project as I want people to find the papers of interest, read a quick summarization and then encourage them to read a selection of papers themselves.

Comment · 9 months ago
As a pathologist and neuro-oncology researcher, to save myself time trying to keep up with scientific literature, I'm working on https://www.summarized.science/ . Based topics of interest (suggestions are more than welcome), the tool queries the scientific literature for each month. Then, by quering some LLMs, it extracts themes and summaries. The tool already saves me time in my day to day life, but still needs a lot of finishing touches to promote actively. Anyhow, it is a lot of time working on a web development "side project" after a hiatus of more than a decade due to residency/PhD-program/kids etc. Input/feedback is more than welcome.
Comment · 4 years ago
Depends on the industry/company but for me it works like this: when the holiday is on a Friday (my day off) it's bad luck and I don't get an extra day. Simultaneously though, when I have to go to a specific conference on a Friday I can switch my day off to a different day in that week since then I will be "forced" to work on my day off.
Comment · 4 years ago
There is no way for us to know if the drug is a "revulotionary cancer drug" if we don't test it in a double blinded randomized controlled trial (RCT). Indeed it would be disappointing the later find out you were treated with the placebo, but so many drugs or other interventions have to potential to be revolutionary but fail to really change the clinical decision making later on.
Comment · 5 years ago
Comment · 5 years ago
I think the appeal to the tidyverse "universe" is the readability of the code. Especially to novel users of R (and there are a lot of people in science that have to generate a plot once a month or so). ggplot2 works fine if you only use that package without the rest of tidyverse. I personally use the data.table package a lot and than generate plots using ggplot2. Stackoverflow is indeed very much focused on tidyverse packages which is a pity as indeed base R can solve so many problems posted too without the need of additional packages.
Comment · 6 years ago
Perhaps aimed at a lower age group, but I think https://www.e-learningforkids.org/ should also be mentioned. They provide free primary school education for all kids. Currently mostly focused on math though.
Comment · 6 years ago
Is there any validation that the user is actually from the selected college? It seems I can write a review about a random dorm just by selecting it. What about using the student’s .edu email address to validate the submission? Just a validation code in the email should be enough. Good luck on the launch though!
Comment · 11 years ago
"My hunch is that Google has a oncology/immunology platform"

As an MD, soon to have a PhD in oncology immunology, I always wonder what project Google could be working on in this area. After all they are a company and most probably try to develop products that will yield a return in the future. So why would someone chose to work for a Google firm that has no real track record in the Life Sciences versus the many life-science companies that already have amazing logistics/experience in place (Novartis, Biogen, Takeda to name just a few in Cambridge, MA). Outside "data-science" projects like genomics, or very technical project like lab-on-a-chip devices, I wouldn't see a big advantage moving to the bay area. However, I guess offering huge salaries always helps convincing people to join your company. And the winters in the Mountain View are probably warmer than the Boston area.

Comment · 11 years ago
Finally a topic on hackernews that I am getting my PhD in..! Anyway, do you have any data indicating what percentage of circRNA is "free" in the plasma versus inside of other entities like platelets or extracellular vesicles (exosomes)?
Comment · 12 years ago
I assume they have to pay taxes over this.
Comment · 12 years ago
A private pilot license (PPL) does not allow for commercial flying (charging passengers). To charge passengers to pilot requires a commercial pilot license.

Live from the official Hacker News API

A modern reader for Hacker News · SvelteKit + Skeleton