movespebp

Joined 2 months ago

Karma

Submissions

Member since

Aug 28

Recent submissions

It's an awful thing to suffer and full sympathy to anyone who does. What unfortunately has happened as well is that the drug companies have successfully convinced the public, providers and sections of the media that any criticism of their products is criticism of people who suffer.

There are very serious concerns about the safety and effectiveness of these drugs, but the companies consistently attempt to misdirect that, seeking to portray the criticisms as "stigmatizing" sufferers or "fear mongering", neither of which is true.

Comment · 2 months ago

That's not true. https://pmc.ncbi.nlm.nih.gov/articles/PMC2719451/ places the figure experiencing side effects at 40%, with 25% reporting those effects as serious. It's also telling that only just under half of those experiencing side effects ever reported those side effects to their providers - likely contributing to doctors getting a skewed perception of the real adverse effects risk.

What's missing is also follow up - for some those effects don't resolve after stopping the drug.

Comment · 2 months ago

I think the issue is informed consent. If people find benefit in them by all means they should be able to take them. But currently these drugs are being given out for the most mundane issues, many of them temporary, after a 2 minute visit with a Primary Provider/GP, with little to no discussion on potentially permanent and serious effects, whether that be long term withdrawal or the equally life ruining PSSD. Neither of which seem to be particularly rare given the number of prescriptions.

Comment · 2 months ago

The sexual side effects can be much much worse, and far more permanent than delayed orgasm or low libido - https://www.pssdnetwork.org

It's also not difficult to spot - the complete removal of libido, sometimes permanently for life, with these drugs has been seen in animal models, and also is not present in other classes of ADs. A lifetime of chemical castration effectively.

Clinicians really have been misinformed about these drugs, the awareness campaigns of the 90s still cast a long shadow, with many not really truly understanding the actual potentially permanent and serious effects of these drugs, or assuming that they're rarer than they are (they aren't rare) - because that's what the pharmaceutical company campaigns have told them.

Comment · 2 months ago

Unfortunately many of the trials look like this : https://study329.org/ - the ghost written study concluded “Paroxetine is generally well tolerated and effective for major depression in adolescents.”

The reality of the actual trial data was very different - with catastrophic results for many.