Recent submissions

Comment · 5 months ago
Antibodies on this scale are not _produced_ by animals. The way these things work is an antibody that binds to a specific target will be _discovered_ by immunizing animals and then screening it's blood or lymph nodes for antibodies of interest. Once an antibody is found and commercialized, it is produced in large bioreactors of cell cultures engineered to produce large amounts of a particular protein (in this case the antibody).

Source: work as a software dev at a company developing antibody drugs

Comment · 1 year ago
Isn't that exactly what they're doing here? My understanding is Deno is asking the courts to invalidate Oracle's JavaScript trademark, making it a generic term in the public domain. They are not asking for the mark to be re-assigned to Deno.
Comment · 2 years ago
It worth noting that the power of the neural engine doubled between the A16 and A17 chips (17 vs 35 TOPS, according to Wikipedia), while the A15 to A16 was a much more modest increase (15.8 to 17 TOPS). So it does seem like they started prioritizing AI/ML performance with the A17 design.
Comment · 2 years ago
Unfortunately, since 2013 Opera is also built on Chromium. They dropped Presto a long time ago.
Comment · 2 years ago
The article says this system in Vancouver has 300% efficiency, so seems like a problem that works a lot better at scale.
Comment · 2 years ago
There's power in bargaining as a collective, whether you're a collective of ten or ten thousand. Either way, it helps with the power imbalance between employees and management.
Comment · 3 years ago
Comment · 3 years ago
I've stopped using Uber in my city (Vancouver) and gone back to traditional taxis because they're providing a more reliable service at equivalent or cheaper prices.

The last few times I've tried to use Uber, immediately after matching with a driver they'll message me telling me to cancel the trip because they don't want to go where I'm going. When I refuse, they'll play chicken and drive around in circles refusing to come pick me up and refusing to cancel themselves if they don't want the job, trying to make me pay the cancellation penalty rather than them. When I fly into YVR, it's so much more convenient to walk to the taxi stand and get a ride home within a few minutes for $50, than to order an Uber, wait 20 minutes for it to arrive, and pay $60-80 for the privilege.

Comment · 3 years ago
Interestingly, there appears to be some localization with that page. I'm in Canada and see:

hello :maple leaf: -> bonjour :fleur-de-lis:

Comment · 3 years ago
That's funny, I tried Go for Advent of Code last year and got through the first 10 days or so without any real difficulty, having never written a line of it before.

Just as there are different spoken/written languages and people find different ones easier or harder to learn based on a huge number of variables, I believe the same is true of programming languages. Sometimes it's the syntax that makes a language difficult, sometimes it's a different paradigm, sometimes it's an unfamiliar memory model or type system -- there are lots of things that can make your brain throw up a block when trying to dive into a new language.

Comment · 3 years ago
I've heard so many people say that Ruby is really easy to pick up and work with and for some reason I've had the exact opposite experience. I have tried to learn Ruby at least three or four times and I bounce off it every time. There are a bunch of other languages that I've learned and worked with effectively, but for some reason my brain just refuses to grok Ruby.
Comment · 3 years ago
The relative costs didn't change for me significantly, I was paying 2600/month USD in rent in the Bay and 2700 CAD in Vancouver, so while it was a significant paycut if you look at the value in USD, the day to day wasn't noticeable.
Comment · 3 years ago
I really liked San Diego when I visited, if I was going to return to the US, I'd seriously consider San Diego.
Comment · 3 years ago
Comment · 3 years ago
My mother was a teacher before she retired to a different state than she'd worked in. She now has to file income taxes in the state she receives the pension from and the state she currently lives in each year.

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