mananatwyndly
Joined 6 years ago
Joined 6 years ago
https://pubmed.ncbi.nlm.nih.gov/21154351/
Another paper discussing the safety of sublingual immunotherapy can be found here:
Sublingual allergen immunotherapy: mode of action and its relationship with the safety profile https://pubmed.ncbi.nlm.nih.gov/22150126/
That number is from the line "SLIT-induced anaphylaxis equate to around one case per 1000 million SLIT administrations or per 526,000 treatment years'.
Another nice review paper can be found here:
https://pubmed.ncbi.nlm.nih.gov/28964530/
Hope this helps!
Manan
For allergy shots/drops your body also makes antibodies to bind to the allergens and prevent them from causing symptoms of the allergens like sneezing or nasal congestion. So both work in a similar mechanism. The challenge with allergy drops and allergy shots is the clinical data shows that it takes a much longer time for your body to create an immune system change that decreases your allergy symptoms than it does for your body to create antibodies to block a virus. Does this make sense?
To start, our goal isn’t home allergy testing- our goal is convenient and accessible immunotherapy for all.
We will work with patients as long as their testing is valid and from a reliable source.
For some patients this means using their existing allergy tests. For other patients who want testing through insurance we will prescribe them a prescription for an immunocap allergy test through a local lab like quest diagnostics. But many patients want the convenience of a home test so we’ve partnered with a highly reliable and clia certified allergy lab to supply home allergy tests. I didn’t just trust the company’s word for it, in fact, many of my friends and family members volunteered to be tested both ways when we tested this out for use in our office and we found the results of the home test to be reliable and accurate.
Unlike allergy shots where the skin testing results affect the initial dose, for sublingual allergy drop immunotherapy the initial dose is incredibly small for everyone for safety, and then escalated up. This is why the combination of symptom history, geographic area and testing can be combined by an experienced doctor to tailor a therapy for you.
Like I do for all of my in office patients that also take at home allergy drops we always educate our patients thoroughly about the risks of treatment and the correct way to use it. We also use the same emergency plan for our patients as we have used in office.
Thankfully in the thousands of patients I, and most of my colleague physicians, have treated this has not been an issue.
I asked about the safety of a drug and the product gave me a summary and literature to answer complex clinical questions fast. This product does a lot of the work that before involved me lots of time clicking and searching and trying tons of different Google searches. For a busy physician it works great.
It saved me time and helped ensure I was using the most up to date research for my decision making. This would’ve been a game changer when I was at an academic hospital doing clinical research, but even as a private physician it’s great to ensure you’re always up to date with the current evidence.
Thank you for the feedback and this all totally makes sense.
Sorry we took a few minutes to get back to this! Unfortunately for HIPAA reason's we cannot use identifying data of patients. This is why we didn't use last names, or patient photos (faces are identifying- and we thought it'd be creepy to do the medical journal thing of putting a black box over the eyes).
We are certainly working on finding patient champions who might feel comfortable being totally public, but there are some legal issues around that.
That said- these are real stories. Also, feel free to google me, Manan Shah MD ENT in Colorado and you can see people's google reviews. Like all review sites, I'm sure you'll find that I didn't click with some people, but in general I'm pleased that most of my patients really had a great experience!
Does this make sense? But I definitely agree, having pretty stock images is something we'll talk to our design team about to avoid the 'marketing scam' feel!
Manan