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Comment · 6 years ago
There is a lot of data that we could study from everyone given the unique expressions of our immune systems. And with many variables that exist, we measure a miniscule few and therefore cannot often get a good picture of chronic health issues. As to your comment downvote, it may rise again. Sometimes trolls and/or people who don't like new ideas will readily dismiss things (here and elsewhere).
Comment · 6 years ago
It's relevant. Mycotoxins (mold produced), and metals can also cause inflammation. In general, it's the immune system trying to sequester or isolate foreign material.
Comment · 6 years ago
I try to dry fast for 15 - 20 hours 1/day per week. I can't really do that for my son and do not recommend it for most children.
Comment · 6 years ago
We try to exclude it from his diet and minimize it in the house, although he's shown no serious anaphylaxis from it. Typo above, he is 7, not 8. At some point trials for food additives would be helpful...for everyone. I certainly cannot speak to all of the stuttering scenarios, but avoiding a few is better than nothing.
Comment · 6 years ago
He is 8 now and minor amounts of annatto, by accident, do not seem to trigger it. We taught him what to look for and avoid anything orangish in color without asking us. I do have a friend whose nephew throws up when he has annatto, but I haven't come across the stuttering connection. I should amend my comment above, we ruled out dairy as a cause given the milk, yogurt, kefir as well.
Comment · 6 years ago
We noticed he was more tentative and starting to stutter around the winter holidays, but could not figure out what the pattern was. Then one early evening before dinner we gave him a slice of organic, orange American cheese (milk, salt, enzymes, annatto). He started stuttering shortly thereafter. He'd had ice cream the previous day with no issues. Then we noticed it after mac'n cheese. Upon reflection, his grandparents brought cheddar duckies to snack on during the holidays. At that point we started eliminating it and did not notice a stutter. Sometimes after pre-school, when he was stuttering, I asked him how his <non-orange> crackers were and he would always say "orange" crackers. We avoided anything obviously "orange" and the problem went away in a number of weeks. It popped up again while eating chicken tenders (cheap ski lodge food) and then we started noticing that the breading in many packaged chicken tenders had annatto for color. The same with cheap vanilla ice cream. He's all good now though -- we were lucky.
Comment · 6 years ago
Neuroquant imaging filters for MRI are supposed to detect changes like this, but are quite expensive and not readily available. The pediatricians shrugged their shoulders. Functional medicine doctors would be more willing to pursue this approach (they like data). The trick is finding the root cause of the swelling, which is usually an immune response to a protein it does not like and wants to isolate. I am unaware of other locations in my son's body that become inflamed by Annatto, his stutter was/is the first notable symptom.

Is it the Annatto itself that collected in my son's brain/frontal lobe and triggered inflammation? A brain scan at that time would probably help shed light.

Was something else there that Annatto reacted with/killed and my son's system inflamed due to the residual proteins (it's used as an anti-parasitic in native cultures - and yes, herbs can cause a die off as most lyme+ patients have demonstrated repeatedly - and I will get forehead pressure from a die-off, my son might be similar in that regard)?

In short, there's not enough data or an easy way to gather it.

Comment · 6 years ago
My young son, now 7 (no stutter), did stutter at age 4 and had some level of anxiety. My wife and I discovered that he has an allergy to annatto, a natural seed used for orange dye & nutty flavor, that triggered the stuttering. The stuttering was likely due to slight inflammation in his brain. In this case, slice of organic American (orange) cheese caused him to stutter within 10 minutes. Then we could tell when he had goldfish crackers for snack at school (dad, they weren't purple crackers, they were orange -- said with a strong stutter). His stuttering disappeared within a couple months of removing annatto foods from his diet. What about the annatto ~triggered inflammation, we do not know (I have an idea, but it's pretty hard to test).
Comment · 6 years ago
Thanks for posting. It lends credence to collecting more data from everyone to better determine T-cell reactivity to a number of pathogens (virus, bacteria, etc) and then let the patients own their data with the freedom/incentive to share that data for research and education. I prefer trying to gather data to identify levels of pre-existing immunities and who is higher risk. The higher risk people could opt for an immune hammer (vaccine).
Comment · 6 years ago
It's good that the athletic departments are getting tests like this done for their athletes to provide more information about systemic damage for symptomatic & asymptomatic infections. Most insurance plans and doctors would not pay/call for MRI imaging for hearts. More systemic testing/data is needed.
Comment · 6 years ago
It's quite possible that if most people owned a solar roof with batteries and redundancy across a specified and localized grid, there would be less need for large power plant owners and fewer donations to political parties. In short, it is easier for politicians to get donations from a small group of people than from a large group.
Comment · 6 years ago
Comment · 6 years ago
I agree. There are so many variables whose interaction is influenced by each individual's unique immune expression, that we need to measure more of those variables for everyone to start identifying common patterns. I would hope that each vaccine volunteer has a minimum amount of testing (>= https://science.sciencemag.org/content/early/2020/07/15/scie...) before and after each vaccine dose. It would also be very beneficial to measure their HLA genetic SNPs (see GSK's MERS vaccine induced narcolepsy in 2009). Transparency and increased measurement of immune data will help improve and/or customize vaccines so that they are effective and safe.
Comment · 6 years ago
Comment · 6 years ago
Are the immune responses to the vaccine identical across the trial group? No. Is everyone's response to sars-cov-2 identical? No. Is everyone's immune system unique in its signaling and adaptive behavior? Yes. How is it possible to correlate immune responses by measuring 0.000x percent of the available data? We do not have complete understanding of our immune systems, thus we need more data and most of it can be relevant.

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