jostmey

The problem was never generating leads. The bottleneck is validated results. It’s performing clinical trials proving efficacy. And this is where I think AI will have the biggest impact—-helping scientist, navigate study complexity and regulatory burden

You know what I call solar--fusion power. There's a giant fusion reactor running for free. We simply need to extract the useful energy. Want to build a terrestrial fusion reactor? A conventional nuclear reactor? You still need to extract useful energy and deal with excess heat. The way I see it, from an economic perspective, long-term, solar wins. Of course, this is just my long-view

I'm surprised there isn't more effort to create hybrids in reverse--an electric car with optional gas generator. The gas generator could run at constant speed, never changing RMP, while the battery handles constant changes in acceleration. The idea is not mine. I've heard about it in China

The tax system in Texas is a better system. Sure, Texas has lots of problems. That doesn't mean there is nothing to learn from Texas.

I live in Texas. I don't like the restrictive laws. Texas could learn a lot for California, just not in the areas of taxation

And why won’t the frontier models continue to become better? The open models are getting better but so are the frontier models. The frontier models might remain in a constant race to remain ahead

I cancelled my ChatGPT account for the restrictions placed on my account, inappropriately flagging about 10% of my queries as unsafe (I was writing grants in immunology). I haven't looked back. I will do the same if with Claude if Anthropic doesn't reverse course soon. What could I use instead? I find Grok very powerful and useful. Also, Google's Gemini, while also have some of the same restrictions, were at least sensible and not blindly blocking my prompts. So Grok and Gemini may be my go to AI's going forward

The real issue isn’t finding therapies but getting them tested in clinical trials

15000 milliseconds! Makes me laugh. I've had the same issue! Usually happens in the morning

I’ve noticed regression and it’s performance too

I am assuming the proposal is to knockout the gene Lim1, which in other animals, creates a brainless phenotype. You won't be able to swap a brain into this headless body (assuming it can fully develop), but this approach could be used for medical research and potentially solve the problem of organ donors, assuming it is ethical

Also, just because Lem1 creates a headless mouse doesn't mean it will do the same in Humans. But I suppose that's what the primate testing will reveal

Claude is only as good as the prompts it’s given

It could still be more fair than no standardized testing