jinder

While the serotonin used in your gut doesn’t directly impact the brain, it does impact the enteric nervous system which communicates via the vagus nerve to your brain. So I don’t think it’s correct to say this doesn’t (or couldn’t) impact your mood (and indeed murine experiments demonstrate it does).

Or perhaps there are significant links demonstrated in murine models of the multi-directional relationship of the gut-brain-immune axis, and that traditional models of disease are not sufficient to elucidate this?

Where is the best-in-class evidence that CBT is effective at treating long covid and chronic fatigue syndrome?

Some people really do have mast cell issues, but everyone and their dog thinks they have MCAS these days and it's questionable in my opinion. Often a diagnosis will be based on whether any of the MCAS-drugs work (rather than testing which is very problematic for MCAS). But as you see in the linked paper famotidine was effective in mice genetically engineered without mast cells, so at least in that instance it's not a mast cell issue.

The tricky thing with increasing butyrate production is that everyone's gut dysbiosis is different - and therefore, a prebiotic that works for one person may make someone else's condition worse. For example, I have big blooms in my Prevotella Copri population which would consume Inulin and make my butyrate production worse - but in people without a Prevotella Copri overgrowth, Inulin would improve their butyrate production.

I would look into 16S microbiome testing (I use Biomesight) and use that as a guide, as well as slowly trialing interventions and monitoring symptoms. None of this is perfect and you kinda have to be on the bleeding edge of science/alternative medicine to figure things out.

What bust are you referring to? As far as I can tell there's still considerable development going on all around London.

How do Christian contemplative traditions predate Buddhism if Buddhism arose in the 5th century BCE?

How have you determined that the excess deaths are due to "covid restrictions" and not for example, long term sequelae of covid itself or other factors?

I think the independent status of the City of London is grossly exaggerated and not really comparable with the Channel Islands.

And what makes you think that?

Er no - the loss of a mother is extremely traumatic to a child. It can lead to long term mental health issues and physical health issues.

To get to the point of re-joining will take a long time with plenty of time for governments and minds in Europe to change.

Ultimately the EU is stronger with the UK as a member, and I’m sure if it’s willing to pay a high enough price it will be let back in (metrication, no-rebate, the euro etc).

I've used SSP and let's just say I think it's nothing short of revolutionary. It seems to be completely changing how my brain works and how quickly it gets activated (in the sense of what state it is in).

Try to be born vaginally rather than c-section (might be too late for that!), avoid antibiotics unless you absolutely need them, polyphenol-rich whole food diet with diverse fruits and vegetables, lots of fibre and resistant starch and fermented foods. Buy organic if possible.