jcims

Joined 12 years ago

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15,846
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5,385
Member since
Mar 6
jcims at crandal.org
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Recent submissions

Comment · 3 days ago
Looks like this is the instragram page of the photographer for the inkjet photo.

It's very obviously not a standard inkjet printer setup, but if you poke around you'll see some custom rigs that make it come together.

Comment · 5 days ago
>Superfluid helium's maximum thermal conductivity is roughly 100x diamond's maximum!

Never thought about this before. Would that mean that heat propagates much more quickly? Possibly even approaching the speed of sound of the material?

Comment · 5 days ago
Looks like you might be getting downvoted but yes!
Comment · 6 days ago
>LLMs drive the cost of making those models down to near zero.

The last place I worked and my current job have a tremendously bureaucratic process for standing up new internally trained models. You could easily spend ten times as much mental energy and effort doing the paperwork and revisiting it annually as you do in the care and feeding of the model itself.

If a canned product meets the requirement, there's a lot to be said for using it. Even if it costs a bit more per decision, the all-in costs are WAY lower.

Comment · 12 days ago
Serious answer - find something that you are so interested in that the problem is you can't stop. Become obsessed.

I went down a similar rabbit hole soon after covid started to build a small, eh, 'hand sanitizer factory' (that's my story and I'm sticking to it). By the time it was done I had a fully automated distillation setup complete with load cells, six different temperature readouts, solid state current control, flow/temp control for liebig condenser recycle, hierarchy of pid loops largely managing output flow and an attempt at live specific gravity testing. That with a nifty little dashboard to show live progress and compare metrics from various runs. Spent a couple grand on it in total and learned a LOT in the process.

Comment · 12 days ago
Side note, I used those same moteus controllers for a decidedly less energetic use case (two axis gimbal for RF satellite tracking) and found them to be super high quality and the lead developer always super helpful. Been a few years but def worth a look if you want to get into motor control.
Comment · 15 days ago
I relate it wasn’t clear in my note. There were no second opinions provided. They basically refused to engage because treatment was already underway.
Comment · 15 days ago
The standard benchmark is five years without recurrence. That plus any side effects of the treatment, surgeries, etc
Comment · 16 days ago
My buddy's gf is allergic to peas.

She visited a friend's house and started getting an itchy throat immediately. Friends knew of her allergy and obviously hadn't prepared any.

Turned out the dog food had peas in it and the bag was open on the other end of the house in the kitchen. (And a supporting role from whatever the dog had slobbered on in the living room)

Sometimes it blows me away how sensitive our bodies can be.

Comment · 16 days ago
>The bigger problem with trials is not the danger, so much as the fact that they're unlikely to do anything.

And? What is the point of this observation? Of course they are unlikely to do anything. Your other option is to do nothing and die. Nothing wrong with that if that's what people choose to do...'accept their fate' and all that. I'm not opposed to it at all, there's a certain appeal to it.

But when your wife and the mother of your two beautiful daughters is laying helpless on nature's altar you fucking move dude. You don't do nothing.

Comment · 16 days ago
Well pointed out and I completely agree with your take.

In our case it was a clinical trial that the oncologist was aware of and we got in. I'd obviously heard of clinical trials but that was my introduction to the machinery by which they operate.

Comment · 16 days ago
This was six years ago, but I found it somewhat unbelievable that there was absolutely no therapeutically relevant guidance from the hospital regarding nutrition.
Comment · 16 days ago
I’m so sorry you’re dealing with this. One thing I would strongly suggest is look for the patient advocacy/advocate for the organization handling your dad’s care. They helped me in one case with my wife’s care, which unfortunately was beset with incompetence and indifference from the start.

Memorial Sloan Kettering is widely considered one of the best treatment centers for gynecological cancers, and they were completely useless for us. The Dr. spent about 15 minutes talking to us and reviewing the case, gave no advice, said nothing in favor of or against the current plan and just said to reach back out after the current treatment plan played out.

This was six years ago and I still can’t think about it much without raising my blood pressure.

Anyway, patient advocate and phone calls/office visits are about the only tools you have. It can be a full time job keeping things on track.

Comment · 16 days ago
That’s definitely one way to look at it.

I would just say that ‘dangerous’ is relative and when the standard of care leaves effectively no hope, your tolerance for risk can change. Yes this does increase that chance of shortsighted decisions or manipulation. That just comes with the territory, I’m still very appreciative that we have the option to elect to participate in the peocess.

Comment · 17 days ago
The second opinion thing has something I learned along the way. Get it BEFORE you have a treatment plan from the initial diagnosis. We got two second opinions (one for her first diagnosis and one for her recurrence) for my wife's ovarian cancer from Cleveland Clinic and MSK and in both cases the doctors would not advise/override the original doctor's treatment plan.

They were complete no-ops and a waste of time. Faced with that same situation today I would simply lie about whether or not a treatment plan was put into place.

Second bit of advice is to try as best you can to go into clinical trials with an understanding of the landscape of disqualifying treatments. Any immunotherapy treatment, for example, will disqualify you from nearly all subsequent clinical trials for immunotherapy.

Lastly the thing I would recommend for partners of loved ones in the crucible, don't get too distracted by trying to 'save the patient' that you miss opportunities stay connected with them in the process. It's not your responsibility to save their life, as much as it might feel that way when you're in the thick of it.

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