icegreentea
Joined 16 years ago
Joined 16 years ago
Being submerged into a 90 degree water bath will probably rapidly hideously wound you and/or kill you.
They show two graphs of protein denaturation curves showing maximum rate change in 50-65 degree range, and a curve of a different protein's hydration shell density changing. At the very least, showing correspondence between hydration shell density and denature curves within a single protein would be significantly more convincing.
While protein folding and interaction is devilishy tricky to compute, the basic idea that injecting extra energy into a system thats held together only by weak hydrogen bonds will disrupt structure and function hardly requires invocation of additional forms of water.
This isn't to say that the claims may not be true. But I would not jump to "probably".
In fact, your quoted statement doesn't even say that proteins become less stable, what the quoted statement says is that a SINGLE protein (lysozyme) undergoes irreversible structural changes over 65 degrees.
We know of a variety of high temperature resistant proteins (Taq Polymerase for example). While is certainly true that most "ordinary" (ie non extremopile) proteins will probably suffer irreversible structural changes in about that temperature change, it's not super great proof.
If OP is right (pretty sure he is), he said that by using something completely free (average weight), we were able to achieve like 50+ years of safe operation of largish commercial airliners. That's amazing.
Also, the problem isn't too much weight per se, it's weight distribution.
I'm not trying to bait you - you're essentially making an argument that relativism in some forms runs into problems when pressed to limits. It's difficult to discuss this without understanding whereabouts you think these limits lie. I don't think anyone can really make an argument about the logical structure of your argument per se, but most will have issues with how you connect various "real world entities" to components of your argument.
In another post I just made an assumption about your beliefs - maybe I was wrong.
And since the OP's culture was clearly a white man's culture - a culture that has been relatively slow to accommodate others, in many ways its still a racist, sexist vision - granted one with unusual bluriness at the edges.
The "real" story is SF has a lower rate of death from heart disease (which is the leading national killer) than usual. And for reference, heart disease and cancer nationally are almost neck and neck (http://www.cdc.gov/nchs/fastats/leading-causes-of-death.htm)
So yeah, it's a useless story.
I think the flip around - ~30% adoption of a newest version at 1-2 years in - especially one that breaks backwards compatibility isn't bad.
I've started numerous python projects at work over the last year all on 2.7. I think we just started the last one. We're finally ready to jump to 3.
Another interesting thing is the entanglement of male personal identity with the corporation. Because men don't actually own fabs - corporations own fabs. Economic/legal entities designed to exploit human labour and creativity own fabs. The very people muttering these statements about real men are doing so while embedding themselves into a matrix of control.
And another way to interpret this - even if a positive vision of masculinity merely includes sufficient self dependence and a capability to provide for others - ie to be free, then this statement is blatantly true. The statement is that people who are truly able to be free are those who own the methods of production - something which the vast majority of men (or people really) in our world do not.
I think both cases are ridiculous, but it's worth separating the two cases.
The sheer inefficiency and ineffectiveness of America's chronic care is not alone. Here in Canada, it's pretty clear that our system strains when put up against chronic care.
There's certainly a lot to fix, but as you've pointed out, doctors are a huge component in the current system that has the change. This points to the fact that somehow we need to engage and get buy in from them.
One of the things that I'm always wary about when reports like this come out is that while they present a wonderful opening into engaging with current stakeholders, it's also very easy to put current stakeholders on the defensive, and have them quickly adopt a us-vs-them mentality, something that certainly is not conducive to change.