gewa

We are still living in a capitalistic society. We have to find a solution which is responsible, safe and returns on the investment. The commercial aspect can be true at the same time.

I agree, and even if it’s both marketing and safety, the safety side has a huge potential downside risk which we have to manage.

Also, just out of curiosity, is there any historical precedent for a nascent, fast growing new industry screaming for self regulation?

It doesn't seem like you are very familiar with German politics or culture, but this is definitely an outlier. Freedom of speech is a central part of our constitution. Defamation is one of the very few ways and enforcement and interpretation is mostly restricted to defamation of policemen. This is the reason why this has resulted in an outcry as the proportionality does not respond to the interpretation how defamation is treated legally.

As a German I have to emphasize that this has no support at all in Germany. The uproar was huge today and its seen as a misuse of power by the politician. Especially as he is not acting as a politician but as representative of the public office of interior. The search warrant needs to be issued by a judge and I'm sure there will be formal investigations how this happened. I would not be surprised if he will be forced to resign. There are also elections happening and misuse of power is seen very badly throughout the people.

This has no support at all in Germany. The uproar was huge today and its seen as a misuse of power by the politician. Especially as he is not acting as a politician but as representative of the public office of interior. The search warrant needs to be issued by a judge and I'm sure there will be formal investigations how this happened. I would not be surprised if he will be forced to resign. There are also elections happening and misuse of power is seen very badly throughout the people.

I agree, the headline is definetly not what the research shows. See my other comment on non-neutralizing antibodies. Please change the title to the original one.

Please note, that neutralization by antibodies is only one of the many possible ways how our immune system can take action. Antibody recognition is still possible with the found mutant:

"To determine whether 501Y.V2 is still recognized by non-neutralizing antibodies, the binding of polyclonal sera (from Fig.2a) to a recombinant 501Y.V2 RBD+SBD1 protein and an RBD+SBD1 from the original lineage was assessed by ELISA (Fig.2b). These data revealed that binding of polyclonal plasma to 501Y.V2 RBD+SBD1 was only substantially affected in a minority of cases (14 of 44 with ≥five-fold reduction, 32%). Most of the convalescent plasma/serum suffered less than four-fold reductions in total binding activity (as measured by area under the curve), suggesting a considerable non-neutralizing antibody component are still able to bind the 501Y.V2 spike antigen"

Please note, that neutralization by antibodies is only one of the many possible ways how our immune system can take action. Antibody recognition is still possible with the found mutant:

"To determine whether 501Y.V2 is still recognized by non-neutralizing antibodies, the binding of polyclonal sera (from Fig.2a) to a recombinant 501Y.V2 RBD+SBD1 protein and an RBD+SBD1 from the original lineage was assessed by ELISA (Fig.2b). These data revealed that binding of polyclonal plasma to 501Y.V2 RBD+SBD1 was only substantially affected in a minority of cases (14 of 44 with ≥five-fold reduction, 32%). Most of the convalescent plasma/serum suffered less than four-fold reductions in total binding activity (as measured by area under the curve), suggesting a considerable non-neutralizing antibody component are still able to bind the 501Y.V2 spike antigen"

Its also worth to note that only 44 plasma samples were used from individuals out of a population where the virus probably originated.

Biochemistry by Jeremy M. Berg, John L. Tymoczko and Lubert Stryer is a widespread introduction to Biochemistry.

Nice to see you on the Frontpage, what an amazing project!. I remember you introduced me to HN 7 years or so ago at some MUN meeting hahaha.

No, the proteins are vitrified very rapidly in liquid ethane at approx. -200°C, so that the structure ist conserved.