Recent submissions

Comment · 6 years ago
Current project: Quarantining myself in my camper van for another week to see if I or my family members are ill before living together.

I have a Mac Mini with upgrades and a 4K monitor waiting.

Also, working on a boro water cooled virtualization/workstation dual EPYC that I've been piecing together before AMD made the press rounds. I'm supposed to have a dual CPU & VRM waterblock but the seller has been deflecting, dodging and dicking around for 4 months... they only mailed half of it.

Comment · 6 years ago
https://www.dotmed.com/listing/ventilator/allied-healthcare/...

10 "in stock," $3,124.01 each.

There's also another model MCV200, 10 "in stock," $5,091.71 each.

Anyone got $95 grand lying around?

Edit: btw, in 2006/2008, the AARC recommended to the White House and/or HHS to buy 10k additional ventilators for the SNS, but the govt failed to do so. Now, the US, is for lack of better adjectives, royally-proper fucked.

https://www.aarc.org/wp-content/uploads/2018/08/issue-paper-...

Comment · 6 years ago
Wasn't Verily supposed to do this, or are they moving too slowly?

Edit: This item's page doesn't work on iPad. After three seconds, the page freezes.

Comment · 6 years ago
Yep, because it's an mAb. EDP1815 is also an mAb. They're expensive and complicated because of big pharma profiteering.
Comment · 6 years ago
Comment · 6 years ago
Camostat plus E-64d was proposed in a paper in Cell around March 5 as a potential superior prophylaxis under investigation because it blockades the virus from using either ACE2 or TMPRSS2, completely denying SARS-CoV-2 from entering human cells.

It's not a vaccine but it seems possible to prevent infection and possibly halt illness. That is, if it doesn't have any yet unknown, horrible side-effects.

Comment · 6 years ago
Hope isn't reality. Overall 20%-50% infection rate is most likely because of the multiple infection waves due to cycles of shutdowns and the extreme infectivity that will occur before a safe and effective vaccine candidate can be manufactured. That maybe 3-5 years. Also, post-resolution immunity duration is unknown.

Furthermore, infection rates in the US aren't being tracked so the CFR denominator is completely unknown.

And, focusing on CFR alone is myopic because of the serious, potentially permanent lung damage that occurs from this virus in those who have "mild" symptoms. There are a plethora of reports of unknown-lasting reductions in lung function by 20-30%.

Comment · 6 years ago
There are only 62k ventilators in the US and 12k held by the SNS. Ventilators aren't simple machines and nowhere near as simple as residential -PAP machines, so this untested "open source" effort or GM saying they would produce them are virtue-signaling, useless noise inapplicable to the present timeframe. And where ventilators are typically used, there are only 65k ICU beds in the US. Furthermore, the machines aren't uniformly distributed. Areas with low ICU beds per capita and large cities will need many more, and some rural areas may not have any ventilators for hundreds of miles.

While there are 140k respiratory therapists in the US, not all of them work in intensive care or hospitals. Nurses are also required to staff an ICU ward.

All of this is moot without PPE needed for medical staff to provide care. No amount of medical robots would be able to tech our way out of this fundamental limitation.

Comment · 6 years ago
I was just talking to my mechanic by text at middlefield & n shoreline at the Arco on the southwest corner, just across 101 from the Googleplex. He may have to permanently close his business and get a regular job because his landlord will demand rent when there are no customers.

A similar situation is happening to Louis Rossmann who doesn't have business interruption insurance because they require flood insurance and weasel out of covering disasters.

Another situation is Michael Moore's nonprofit movie theaters won't be reimbursed to pay or govt pay their employees' salaries, and building lease/rent.

Also, tip-based workers are screwed too.

Only 20% of workers are getting some money, with a little promise of temporary UBI to some people.

And then the government has the gall to offer interest-bearing loans instead of no interest loans and grants? WTF!

The situation is there will be people working to put food on the table sick or not, and riots if people aren't made whole. The US economy will crash and burn for decades if this isn't handled correctly by clawing back some of the tens of trillions the MIC, corporations, and the rich stole from the little guys and regular folks.

Comment · 6 years ago
So the EE/CS undergrad program I did was heavily-analytical:

- It included the entire advanced level chem, physics and stats series for scientists and engineers.

- It was two elective courses shy of a math degree, including abstract math, concrete math, and tensor math.

- Only a few courses shy of a physics degree as well.

- The entire EE track and entire CS track of course.

- Writing lots of code for multiplatform portable code including Linux, HP-UX, Solaris, SGI, and some MINIX 2.

I think they should make it a mandatory combined undergrad /Masters' or /PhD program to be of sufficient depth into research achievement and breadth of knowledge to be useful in industry that cannot be achieved in the absence of an advanced degree. I think most of the undergrad CS knowledge can be acquired by osmosis in industry or self-study without a degree.

Comment · 6 years ago
I'm glad I didn't study at all or have any coaching for the 1600 pt SAT I in the mid 90's because it would've been entirely unnecessary. I missed one question on the math section and it was a dumb mistake on my part. Our school's graduating class alone had over a dozen perfect SATs, multiple full rides to Harvard/MIT/Stanford and around 70 over 1500. ~97% had test prep.

Now go to India, take the JEE and find out how fun testing can be because the SAT is not much harder than a driving test. :) (Emphasis on the JEE being a much better measure because it's more difficult and more voluminous so that it would make Einstein feel insecure and inadequate.)

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