bpizzi

To my knowledge, it doesn't.

On Emacs there's gptel which integrates quiet nicely different LLM inside Emacs, including a local Ollama.

> gptel is a simple Large Language Model chat client for Emacs, with support for multiple models and backends. It works in the spirit of Emacs, available at any time and uniformly in any buffer.

Zone 2 is all about giving the mitochondries a chance to get better at providing a steady energy flow over a long time, mainly by optimizing for burning fat as fuel instead of glucose, avoiding lactate accumulation during the process [3].

In between, in zones 3 & 4, you get a little of both those ends of the spectrum, it's still helpful to a degree, but it's not really optimized: that why it's deemed preferable to spend the bulk of your training time in either your zone 2 or zone 5.

The ideal composition of a training period seems like 90% zone 2 and 10% zone 5, and going for more than 1h of zone 5 per week seems not that interesting. Also, mixing zone 2 and zone 5 in the same training session is not ideal, it's better to stay focused on one thing at at time.

Obviously, as science is what it is (and that's a good thing), those study are debatable and do have weak spots.

You may want to take a look at this meta-study [0].

> “A meta-analysis of prospective epidemiologic studies showed that there is no significant evidence for concluding that dietary saturated fat is associated with an increased risk of CHD or CVD.”

Well, in my mind `epigenetic = biological age * food intake`, where `food intake` is 'is he eating a consistent healthy diet, given that a typical person not eating healthy will surely says that she's eating healthy'. It's (unfortunately) enough to be >30yo, having bad genes around cholesterol handling pathways and eating a standard american diet (even without significant overweight) to be in the danger zone in terms of cardiovascular risks.

ApoB in the golden (and recent) blood test here. OP: given that you have experienced chest pains, and if it's not the case already, go have your ApoB checked and ask for statins if needed: your 60yo you will thank you.

And, in my own and non-important opinion: don't waste your time even thinking about potential link between your condition and covid/vaccine, this is a path that leads nowhere in terms of prevention of futures attacks.