biomcgary

Joined 14 years ago

Karma
2,554
Submissions
684
Member since
Aug 29
Computational biologist. Modeling individual human health using multi-omic approaches and machine learning. Searching for islands of causality in seas of correlation. Cross-species translation of biological systems: Of mice and men (and zebrafish, worms and yeast).
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Recent submissions

Comment · 4 months ago
My teenage boys are hooked on Calvin & Hobbes.
Comment · 4 months ago
Comment · 4 months ago
But, datacenter development in space does not deal with local NIMBYs, just centralized decision-makers that are easier to "influence".
Comment · 5 months ago
Gives new meaning to "gut intuition", since the superparamagnetic macrophages are in the liver.
Comment · 5 months ago
My CEO did a deep dive into AI prototyping and eventually ran into a wall with data architecture and deployment. Fortunately, he realized very quickly that having human designed core infrastructure is what enables vibe coding that doesn't run off the rails.
Comment · 6 months ago
Your username is uncanny for this comment. Well played.
Comment · 7 months ago
The fact that you aren't persuaded is the evidence of collapse. Previous generations of LLMs persuaded everyone of anything.
Comment · 7 months ago
I'm a non-Conformist is the historic sense. In the past decades, American Christianity has devolved into a smorgasbord of personality cults and group therapy that effectively suppresses the freedoms that many Christians fought for at the country's founding. Not usually overtly, but the prison is in the mind (or its lack of use).
Comment · 8 months ago
Do you know if any of these multi-stage approaches can run on an 8gb M1 Air?
Comment · 10 months ago
Computational biologist with a focus on predicting individual human health at a startup, but I have ended up managing software engineers. (Scientist explore and engineers make the science work in production.)
Comment · 10 months ago
This explains the Scotch-Irish settling in Appalachia. It felt like home, but without the overbearing Brits nearby.
Comment · 10 months ago
The Readme for a UI library benefits enormously from screenshots, even terminal based UIs.
Comment · 1 year ago
The mind-body link is too important to get the causality wrong and The Body Keeps Score is an ideology where the causality only goes one way.

I have a cousin that had frequent, overwhelming anxiety attacks. She started eating breakfast consistently and the anxiety disappeared at the same time. Anxiety is strongly linked to gut activity, so the temporal correlation is a smoking gun, even if not dispositive.

For her, "understanding past trauma" was irrelevant to the solution.

Comment · 1 year ago
Billions of cell derived from Henrietta Lacks agree with you.
Comment · 1 year ago
I think you are getting at the need for tiered layers of abstraction and constraint. Simultaneously considering all possible ways to solve a problem doesn't work for humans or the LLMs derived from our use of language. The repeated use of Domain Specific Languages (DSL) in the context of a general purpose programming language gets at this same need to constrain solution spaces within a reasonable boundary.

Once we have quantum LLMs, the need for intermediate abstraction layers might change, but that's very [insert magic here].

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