atrexler

right

I've no idea about the fasting stuff. Just thought its important to make clear this particular study is all about doing stuff to cells or lumps of cells in dishes (again sorry if I missed more involved model system in the paper). Whether thats a good model for cancer in people and how fasting interacts with that I honestly have no idea.

Well, to be precise- this study shows no evidence of a fasting effect.

they show if you starve cells in a dish in a way that might mimic what happens when you fast, you can kill the cells. I didn't see any mention of even mouse studies in there, so I don't know what their in vivo model was but it mostly looks like cell culture to me (apologies if I've missed that). Extrapolating that to humans is extremely hard.

For sure a promising result but its pretty preliminary.

this isn't how chemotherapy works. traditional chemo targets rapidly dividing cells in the body: cancer, hair/skin, intestinal lining cells. That's why you get those side-effects.

+1! New go-to for suggesting there's evidence you're about to have a bad time.

Overload your gels much bro?

JK- just looking for those impurities.

"Who's more foolish, the fool or the fool who follows him?"

I wonder at how this would vary across industries and also company sizes. I'm surprised the study had positive results at a relatively large firm. I think its easy to imagine working-from-home gains in small firms and startups where typically there's a much stronger selection for highly motivated and enthusiastic people. It's not clear the same would result in a huge firm where you have less of that selection.

Also how does one measure productivity? (this is probably a naive question as a relative neophyte) An article I found on this says they were 13.5% "more efficient" but I'd love to get the details on what that means. Its a travel agency so are they just booking, scheduling, organizing, etc? Would love to see a similar study in a SW dev environment, alternately something less tech focused but collaborative...I dunno but something creative most likely.

I'm currently using Asana for task management. I guess the only upside is that I can share tasks with my wife, but its clearly not really meant for just single person management.

Has anyone tried both taskwarrior and asana? Any obvious pros/cons?

taskwarrior seems much simpler and can live locally if you dont want locked in asana/whatever?

beware survivor bias on this thread.

The proteins that organize DNA, called histones, can be chemically modified in a variety of ways. The modifications have the effect of turning on/off stretches of the DNA simply by modifying its physical structure (the way the dna is arranged and packed around the histones). There are tons more mods that can happen which have a variety of effects (for example, tune the amount that a gene is expressed). This is called epigenetics if you want to google more.

If you've heard of those studies where if your grandparents experienced a famine it makes some difference in your genetics, one hypothesis is that its caused by this.

Absolutely agree with your point. I don't think the practice in any industry (trucking, healthcare or distribution centers) is okay but I'm simply pointing out its not a unique problem.

Sure, I can't tell you about white collar folks pissing in bottles, I may have exaggerated there.

But in healthcare (for nurses, therapists, aides) its quite prevalent that people don't drink/eat enough at work nor do they take proscribed breaks because productivity standards are so high.

Look I'm not saying its right or fair or good. I'm simply pointing out that its not unique to Amazon.