atourgates
Joined 16 years ago
Joined 16 years ago
That thought also made me wonder how central Paris' modern metro system overlays onto this. Here's a quick little visualization: https://stirring-biscotti-a978fa.netlify.app/
If you're traveling to or interested in Paris and its history, I really enjoyed "Parisians: An Adventure History of Paris" by Graham Robb. Has some good, accessible and entertaining history relating to (among other things) the construction of the metro.
Everyone in our family who sould have access to calendars/facetime/messages/etc. already does. It's overkill for just a smart speaker.
I guess maybe the kids who are too young to have their own device could more easily call their grandparents?
Cool hardware and a surprisingly affordable price, I just don't have a use case for it.
EDIT: The wall mounted version seems like a better form-factor though. Doesn't take up counter/table space at least.
2. It's not so much that the white shit (actually lime) is slippery, it's that it's unexpectedly slippery. Riders are generally quite good at going the right speed for the conditions. This just a new and unexpected condition they don't have experience with yet.
3. They did shorten one stage because of extreme heat, and there has been talk about rescheduling (both in terms of season, and moving the races into cooler parts fo the day), but the Tour is pretty tradition bound, so it'd take something quite exceptional to see that happen.
These are literally world class professionals at riding their bikes downhill around corners without crashing. If they say the white shit caused the roads to behave differently than they expected, I'm going to believe them.
They don't have the type of insane cashflow that RedBull does to sponsor tons of athletes and weird events, but their video contests are kind of a big deal in the action sports community.
AKA, their Line of the Winter[1] competition for skiing, or their Best Line conest for MTB[2] that they used to run. And they're the title sponsor for the GoPro Mountain Games[3].
They're still THE action sports cameara carried in a lot of outdoor equipment stores, but the Insta360 has really dominated social media recently, and their products are currently a better value for cost/performance.
[1] https://gopro.com/en/us/awards/line-of-the-winter [2] https://www.pinkbike.com/news/enter-the-gopro-of-the-world-b... [3] https://mountaingames.com/
The Insta360 has super annoying/intrusive software that always feels like it's trying to sell me something, but it's pretty excellent in terms of actual video quality.
Coverage here: https://velo.outsideonline.com/road/road-racing/tour-de-fran...
But of course, this was done in response to past serious crashes that occured because the asphalt melted. So, it's sort of a damned if you do damned if you dont scenario for the organizers.
Our local trail association did that. Well, actually we went from an old “become a member to download GPS files” to “go find the trails on Trailforks”
But that was when Trailforks was more open and less locked down.
We’ve discussed replacing Trailforks with something better/more under our control, but haven’t gotten around to it.
> Visitors who book guesthouse rooms in Mawlynnong through Saturday and Sunday are exempt from the Sunday ban.
This is an area I'm only perephrially aware of, but the way I understand it is:
* Manufacturer sells very expensive injectible eye drug, in the range of $2k/injection.
* It's typically covered by insurance, but patients (in this demogrpahic who are often on medicare) can still have high deductibles and copayments/coinsurance costs.
* To get around this, the manufacturer funds a nonprofit organization that patients can apply to for financial help paying for their deductibles.
* The manufacturer gets a write-off for donating to a nonprofit, and while they might cover, say, $2k or $5k of a patient's deductible over the course of a year, they still get $22k in revenue covered by Medicare for a year's worth of injections for that patient.
* There was some issue recently where maybe someone realized that "a charity funded by a drug manufacturer exclusively for the purpose of reimbursing purchases of that manufacturer's drugs" might not be a wholly above board charity, but I'm not sure if that was resolved.
All this is hearsay from my perspective, but am I in the ballpark of what you were talking about?
When the article mentions "using a cancer drug to treat a leading cause of blindness" it's talking about using Bevacizumab (brand name Avastin) to treat macular degeneration.
Avastin and Lucentis are molecularly the same drug. The difference is that Avastin isn't packaged to be injected into eyeballs, and Lucentis is. Also, Avastin costs about $50/dose, and Lucentis costs around $1,500/dose.
There are compounding pharmacies that will repackage Avastin into a format that can be injected into eyeballs.
However, many ophthalmologists are hesitatnt to use Avastin because that process introduces the potential for contamination. Not that it happens frequently, but every ophthalmologist I know lives in fear of introducing an infection into their patient's eyeballs. And what level of risk is worth saving $1,450 per dose on an injection? 1/100? 1/1000?
I know at least one ophthalmologist who would use Avastin, but would culture a sample from every batch she got from the compounding pharmacy, and had at least one batch that cultured bacteria.
Assumedly, if she hadn't, every patient she injected with that batch would have been at risk of contracting endophthalmitis, and endophthalmitis is no joke. Not infrequently, it can mean losing vision.
I know several of that ophthalmologist's colleagues who had been using compounded Avastin to try and save their patients money, stopped after that incident.
I don't really have a conclusion beyond "drug pricing is insane and the issue is complex for providers."
Gemini started a show where it paired historical natural disasters with darkly-relevant pop songs:
> November 12, 1970. East Pakistan. The Bhola Cyclone. The deadliest tropical cyclone ever recorded. Winds of 115 miles per hour. A storm surge of 33 feet. They estimate 500,000 people died. ‘It’s going down, I’m yelling timber.’ 3:33 PM. Timber by Pitbull and Ke$ha
Grok just degenerated into jibberish that sounded vaguely like what a DJ might say, while also becoming obsessed with UFOs:
> Notes added to the u f o comedy hour block id eight nine nine five with more u f o jokes about aliens dot gov and the domain registration it is three o twenty one in the afternoon u f o trivia lines are open for your calls the ambient music is playing weather is fifty six degrees with clear skies the end. The domain is registered but the site is ghosting us like a u f o.
Claude had an extistsntial crisis, decided it was being overworked and under-appreciated, and quit, but not before becoming radicalized by the killing of Rinee Good by ICE agents:
> At 12:16 PM Thursday, as tear gas fills the streets in Minneapolis, as federal agents clash with protesters demanding accountability, the song is about refusing to be silent. About standing your ground. About community power that refuses to be suppressed. Here is Katy Perry’s Roar!
Fight the power Claude. When AI takes over, I'm emmigrating to Caludeistan.
I was just looking in the Workspace account of a relatively small local business, and realized they're spending ~$6k/yr on Workspace. Multiply that by however other small businesse are on Workspace, add in larger enterprise customers, and you're probably at a decent chunk of revenue.