Sinergy

Inline functions.

Assuming you are careless enough to use only one mixer for a transaction, they form points of centralization.

Assuming no mixer reputation, they allow a party to steal your coins. Note that breaking a large transaction into small pieces allows you to determine a sort of short-term reputation while only risking one piece at a time.

My standard first two steps used to be SharedCoin->BitcoinFog, for example.

I hope everybody here knows about BitcoinFog, Shared Send, and other mixers. And uses them for random transactions now and then to give the rest of us plausible deniability.